Genesis Molecular AI · 1 day ago
Principal CADD Scientist
San Diego, CA
Full-time
Hybrid
Senior Level, Lead/Staff
5+ years expGenesis Molecular AI is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Principal CADD Scientist to join our team, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US.
Artificial Intelligence (AI)BiotechnologyInformation Technology
Responsibilities
Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents
Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts
Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches
Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making
Adapt to a fast-paced environment where innovation and quick iteration are encouraged
Qualification
Required
PhD in Computational Chemistry, Structural Biology, or a related field
Deep understanding of structure-based drug design and protein-ligand interactions
Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite
Minimum of 5+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs
Onsite in our San Diego lab is preferred for this role, to be able to collaborate with our scientists
Benefits
Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees)
Stock Option Eligibility
401(k) Plan
Open PTO Policy
Paid Company Holidays
Subsidized lunch and snacks at our offices
Company
Genesis Molecular AI
Genesis Therapeutics unifies AI and biotech to accelerate the discovery of new medicines.
51-200 employees
H1B Sponsorship
Genesis Molecular AI has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2024 (1)
2023 (1)
2022 (1)
Funding
Current Stage
Growth StageTotal Funding
$256.1MKey Investors
Andreessen HorowitzRock Springs Capital
2023-08-21Series B· $200M
2020-12-02Series A· $52M
2020-04-01Series Unknown
Leadership Team
Evan Feinberg
Founder and CEO
Aleksandra Faust
Chief AI Officer
Recent News
Genetic Engineering News
2025-12-10
MIT Technology Review
2025-11-27
Company data provided by crunchbase