Cincinnati Children's Office of Academic Affairs and Career Development · 2 months ago
Bioinformatics Analyst
Cincinnati, OH
Full-time
Onsite
New Grad, Entry Level
0+ years expCincinnati Children's Hospital Medical Center is committed to advancing precision medicine and delivering timely, accurate genetic and genomic insights. They are seeking a Bioinformatics Analyst to support complex genetic and genomic tests by optimizing workflows, supporting lab directors, and implementing innovative tools to improve patient outcomes.
Hospital & Health Care
Responsibilities
Execute and monitor data analysis pipelines (e.g., sequence alignment, variant calling, sample identity) for laboratory generated data (e.g., NGS, microarray)
Work with laboratory and clinical teams (e.g., lab directors, wet-lab technicians, genetic counselors, genomic scientists, and clinicians) to verify results consistent with lab SOPs and meet turnaround time requirements
Monitor bioinformatics work queues to ensure cases are processed and moved on in a timely fashion
Responsible for identifying and resolving testing discrepancies and ensuring timely handling of urgent clinical laboratory requests
Support quality control (QC) of laboratory generated data and ensure accuracy and completeness
Ensure data are securely stored yet highly accessible to authorized users
Maintain and troubleshoot existing bioinformatics workflows
Contribute to laboratory documentation (e.g., test validation reports, change logs) to meeting clinical regulatory standards (e.g., CAP)
Maintain accurate records of analyses, software versions, and databases used
Contribute to the evaluation and development of new software solutions to support lab testing and improve workflow performance
Work with senior clinical bioinformaticians to support the development, validation and deployment of analysis pipelines for new clinical lab tests
Develop new applications as clinical testing modules for in-house Laboratory Management System
Utilize project and time management skills to complete projects within specific timeframes
Utilize version control system for all code changes and adhere to strict deployment guidelines
Interface with laboratory and clinical teams to collect requirements of basic to moderate complexity, including user workflows
Work closely with other teams (e.g., IT staff) outside of laboratory for addressing data analysis issues
Communicate with third party software and platform companies (Illumina, Fabric Enterprise, Bionano, SOPHiA Genetics, etc) to ensure workflow and pipeline updates, bug fixes, and processing changes are reviewed and implemented properly
Contribute to analysis reports and figures for publications
Qualification
Required
Bachelor's degree in a related field required
0+ years of work experience in a related job discipline (entry-level applicants with relevant training are encouraged to apply)
Preferred
Education: B.S. or M.S. in Bioinformatics, Computational Biology, Biomedical Informatics, Data Science, Systems Biology, or a related field
Programming & Systems: Proficiency in Linux/Unix command line and scripting languages (Python, Bash, or R); experience with High Performance Computing clusters and version control platforms (Bitbucket, Git, GitHub)
Professional Skills: Detail-oriented with excellent documentation and communication abilities
Bioinformatics Analysis: Hands-on experience analyzing NGS and microarray data; familiarity with bioinformatics tools such as DRAGEN, BWA, GATK, samtools, IGV, and Manta
Data & Database Management: Experience with database table design, SQL, and bioinformatics databases such as ClinVar, ClinGene, gnomAD, and OMIM
Clinical & Laboratory Experience: Familiarity with clinical lab testing workflows and experience working in CAP-certified environments; understanding of molecular diagnostic processes and clinical time constraints
Software & Technology: Experience with workflow management systems (Nextflow, Snakemake, containerization), web development (PHP, JavaScript/jQuery/AJAX), and data integration using Mirth Connect
Advanced Computing: Experience applying cloud computing and machine learning techniques to biomedical data
Benefits
Medical coverage starting day one of employment. View employee benefits here.
Competitive retirement plans
Tuition reimbursement for continuing education
Expansive employee discount programs through our many community partners
Shift Differential, Weekend Differential, and Weekend Option Pay Programs for qualified positions
Support through Employee Resource Groups such as African American Professionals Advisory Council, Asian Cultural and Professional Group, EQUAL - LGBTQA Resource Group, Juntos - Hispanic/Latin Resource Group, Veterans and Military Family Advocacy Network, and Young Professionals (YP) Resource Group
Physical and mental health wellness programs
Relocation assistance available for qualified positions
Benefits may vary based on FTE Status and Position Type
Company
Cincinnati Children's Office of Academic Affairs and Career Development
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Cincinnati, Ohio, US
5001-10000 employees
Funding
Current Stage
Late StageCompany data provided by crunchbase