Mount Sinai Morningside · 2 months ago
Postdoctoral Fellow-MSH-30030-279
Mount Sinai Morningside is one of the largest academic medical systems in the New York metro area, and they are seeking a Postdoctoral Fellow to engage in translational research projects focused on host-pathogen interactions and vaccine responses. The role involves working with various preclinical animal models and conducting immune profiling and serological assays in a laboratory setting.
Hospital & Health Care
Responsibilities
The postdoc will be involved in translational research projects that study host-pathogen interactions and host-vaccine responses in preclinical animal models
The research projects include work with guinea pigs, hamsters, mice and human primary cell cultures in BSL2/3/3+ facilities with SARS-CoV-2 and influenza virus
The aim of these studies is to find correlates of protection and understand host immune responses to viral infection and vaccination in different models
Special focus will be on immune profiling of mouse lungs in mice with skewed host immune responses upon respiratory infections
This work will be done at bio safety levels 2 (influenza virus) and 3 (SARS-CoV-2) in the lab
Hamster intranasal vaccination
Adjuvant formulation and vaccine admixing
Virus titration from nasal turbinates and lungs in preclinical animal models
Setting up preclinical infection models with influenza virus and coronaviruses
Serological assays (ELISA, microneutralization assays, ADCC assays, ADCP assays)
Cellular mediated immunity assays (ELISPOT, flow cytometry)
(Single cell) immune profiling (flow cytometry, single cell and bulk RNAseq, luminex cytokine ELISA, …) and assist with multi-OMICS data acquisition and analysis
Qualification
Required
PhD required
Experience with handling mice in BSL2 environments
Sample preparation for OMICS data generation
Experience with serological assays (ELISA) and single cell techniques (flow cytometry, RNA seq,… )
OMICs data analysis with standard analysis pipelines
Company
Mount Sinai Morningside
At Mount Sinai Morningside, we offer exceptional clinical care and research within the comfort of a neighborhood hospital known for compassion and sensitivity.
H1B Sponsorship
Mount Sinai Morningside has a track record of offering H1B sponsorships. Please note that this does not
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2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)
Funding
Current Stage
Late StageLeadership Team
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