Research Scientist jobs in United States
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Exact Sciences · 19 hours ago

Research Scientist

Exact Sciences is a company focused on transforming cancer detection and treatment. The Research Scientist will be responsible for designing and executing experiments, analyzing results, and contributing to the development of diagnostic assay products using DNA sequencing methods.

BiotechnologyHealth DiagnosticsManufacturingMedical
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Responsibilities

Conduct bench level experiments within several product or technology areas and identify problems and discrepancies
Independently plan and analyze results of bench level experiments within several product or technology areas: effectively present at data meetings, group meetings, and project team meetings
Operate scientific instrumentation related to performance of duties and notify appropriate personnel of any problems
Effectively utilize and apply methods or technologies and provide ideas for new techniques, when appropriate
Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures
Provide technical input and participate in decisions affecting project planning and experimental design
Prepare and provide information and data for scientific abstracts/conferences/project meetings/publication
Generate, document, and communicate development plans for critical aspects of a project
Participate in the development of research plans and experimental outlines, write experimental protocols, and perform laboratory experiments
Prepare detailed technical procedures, protocols, and reports
Evaluate impact of nonconforming data to product or process
Identify and address trends in study data
Prepare and approve written reports
Lead identification of areas for process improvements
Maintain lab notebook in a complete and consistent manner, following all legal, ISO, and QSR requirements, as well as keeping clear and complete
Prepare reports and documentation providing the analysis or summarization of experimental results, outcomes, and next steps to supervisor, technical teams/groups, or project teams
Present experimental results and defend scientific ideas and findings at project or departmental meetings; provide technical input, as needed
Work on problems of diverse and complex in-scope in which analysis of data requires evaluation of identifiable factors
Exercise judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions
Work on individual assignments and with project team members, as appropriate, to meet department and project objectives
Work within project timeframes that are established collaboratively by team members
Act as technical leader for one or more projects that are moderate to complex in scope
Exercise discretion and independent judgement within broadly defined practices and policies in selecting methods, techniques, and evaluation criteria for obtaining and interpreting results, analyzing data, and presenting findings in a professional and knowledgeable manner
Promote an open, collaborative environment built on trust to foster positive teamwork
Assist in planning and recommendation of activities that account for prioritization of organizational and department goals
Ability to train and mentor research associates
Ability to organize, present, and convey moderate problems or issues
Ability to communicate clearly with supervisor and group members
Excellent presentation skills
Ability to collaborate, work effectively and contribute within team, department, and cross-functional teams
Strong attention to detail skills
Ability to effectively work on several varied projects at one time, with frequent changing priorities
Excellent analytical, problem solving, and decision-making skills
Apply technical knowledge, scientific creativity and rigor, collaboration with others, and independent thought; ability to provide insights and defend scientific ideas
Apply experimental knowledge and outcomes to new and valuable problems; ability to make predictions based on a deep understanding of the fundamental nature of the inputs into a decision or action
Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork
Support and comply with the company’s Quality Management System policies and procedures
Regular and reliable attendance
Ability to lift up to 20 pounds for approximately 5% of a typical working day
Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 50% of a typical working day
Ability to grasp with both hands; pinch with thumb and forefinger; turn with hand/arm; reach above shoulder height
Ability to comply with any applicable personal protective equipment requirements
Ability to use various types of laboratory equipment including microscopes, microtomes, blades, strainers, and pipettes for extended periods of time
May perform repetitious actions using lab tools
Ability to use near vision to view samples at close range
May be exposed to hazardous materials, tissue specimens and instruments with moving parts, lasers, heating and freezing elements, and high-speed centrifugation
Ability and means to travel between local Exact Sciences locations
Ability to travel 5% of working time away from work location, may include overnight/weekend travel

Qualification

Molecular biology techniquesNext-generation sequencing (NGS)DNA extractionGMPISO knowledgeStatistical software (JMP)DNA library constructionAnalytical skillsProblem-solving skillsTeam collaborationPresentation skills

Required

PhD in life sciences, medical technology, clinical laboratory science, chemical/physical/biological science, or related field; or Master's degree in life sciences, medical technology, clinical laboratory science, chemical/physical/biological science, or related field and 4 years of related experience in lieu of a PhD; or Bachelor's degree in life sciences, medical technology, clinical laboratory science, chemical/physical/biological science, or related field and 6 years of related experience in lieu of PhD
1+ years of experience in medical device/IVD, biotech, life science, or pharmaceutical industry
Demonstrated ability to apply molecular biology and/or biochemical techniques
Demonstrated understanding of GMP, ISO, and Quality Systems
Good knowledge of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics
Basic knowledge of statistical and mathematical methods in biology/genetics/genomics; including experience with statistical software, such as JMP
Proficient computer skills to include Internet navigation, Email usage, and word processing
Proficient in Microsoft Office to include Excel, Word, and PowerPoint
Demonstrated ability to perform the Essential Duties of the position with or without accommodation
Applicants must be currently authorized to work in country where work will be performed on a full-time or part-time basis. We are unable to sponsor or take over sponsorship of employment visas currently

Preferred

2+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry
Hands-on experience with DNA extraction, quantification, and physical analysis (e.g. electrophoresis or spectrophotometry)
Experience with NGS based diagnostic assay development is desirable
Experience with R, Python, or other advanced data analysis tools is desirable
Demonstrated ability to plan, execute, analyze, and interpret experiments
Good documentation practices
Hands-on experience with DNA library construction and target enrichment for analysis on Next Generation Sequencing platforms
Experience with cfDNA-based assays and automation platforms
Familiarity with assay development, optimization, and validation processes
Proven ability to work cross-functionally with R&D, bioinformatics, clinical operations, and quality teams
Knowledge of cancer biology, genetics, genomics, and/or epigenetics

Benefits

Paid time off (including days for vacation, holidays, volunteering, and personal time)
Paid leave for parents and caregivers
A retirement savings plan
Wellness support
Health benefits including medical, prescription drug, dental, and vision coverage

Company

Exact Sciences

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Exact Sciences offers a portfolio of cancer screening and diagnostic tests that span from early detection to treatment monitoring.

Funding

Current Stage
Public Company
Total Funding
$2.75B
2025-06-20Acquired
2024-04-11Post Ipo Debt· $620.7M
2023-02-23Post Ipo Debt· $500M

Leadership Team

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Kevin Conroy
Chairman & CEO
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Aaron Bloomer
Executive Vice President, CFO
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Company data provided by crunchbase