Jobs via Dice ยท 13 hours ago
Scientist - Cell-Based Assays
Rahway, NJ
Contract
Onsite
Mid, Senior Level
3+ years expTalent Software Services is in search of a Scientist - Cell-Based Assays for a contract position in Rahway, NJ. The role involves executing high-throughput cell-based assays, maintaining mammalian cell lines, and collaborating with discovery teams to deliver high-quality results for discovery programs.
Computer Software
Responsibilities
Maintain, expand, and plate mammalian cell lines for 384-well assays
Set up and execute assays with compound dispensing via Labcyte/Beckman Echo
Run and optimize detection formats (e.g., luminescence, cAMP, HTRF/TR-FRET, fluorescence)
Generate dose-response curves (4-parameter logistic fits) and report EC50/IC50 with QC
Troubleshoot assay performance, optimize Z factors, and document SOPs/results
Collaborate with discovery teams to prioritize studies and timelines
Additional responsibilities may include setting up western blot assays and learning how to run in-cell westerns
Qualification
Required
BS/MS/PHD in Biology, Pharmacology, Biochemistry, or related field; BS with 5+ years, Masters with 3+ years and PHD with 1+ year of industry or equivalent lab experience
Proficiency in mammalian cell culture and 384-well assay workflows
Experience with plate readers and assay platforms (e.g., cAMP, HTRF, luminescent assays)
Strong data analysis skills: 4PL curve fitting, EC50/IC50 determination, and curve QC (e.g., R^2, top/bottom constraints)
Detail-oriented, organized, and comfortable in a fast-paced, high-throughput environment
Preferred
Experience with automation/LIQ handlers, LIMS/ELN, and statistical QC (Z , CV, S/B)
Familiarity with GraphPad Prism, ActivityBase, or equivalent analysis tools
Hands-on experience with Echo acoustic dispensing
Company
Jobs via Dice
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0-1 employees
Funding
Current Stage
Early StageCompany data provided by crunchbase