University of California, San Francisco · 19 hours ago
Levine Lab - Electrophysiologist (Assistant Professional Researcher)
The University of California, San Francisco is seeking a skilled and motivated Electrophysiologist for the Levine Lab. The role involves conducting electrophysiological experiments, utilizing calcium imaging techniques, and collaborating with cross-disciplinary teams to investigate ion channel properties and their role in pain sensation.
AssociationBiotechnologyEducationMedicalPharmaceutical
Responsibilities
Conduct electrophysiological experiments using patch-clamp techniques to investigate ion channel properties and gating mechanisms in sensory neurons
Use calcium imaging techniques (e.g., Fura-2, Fluo-4, GCaMP) to study intracellular calcium dynamics nociceptors
Investigate the role of ion channels in pain sensation and neural signaling by examining neuronal responses to pharmacological agents and mechanical, thermal, and chemical nociceptive stimuli
Utilize primary human sensory neurons to study specific ion channel function
Analyze large datasets from electrophysiology, imaging, and molecular experiments using appropriate software (e.g., MATLAB, Clampfit, ImageJ)
Work alongside cross-disciplinary teams, including pharmacologists, molecular biologists, and computational biologists, to achieve research objectives
Prepare research reports, manuscripts for publication, and contribute to grant writing and lab compliance (e.g., IACUC, biohazard, BUA)
Qualification
Required
Doctorate in Physiology, Neuroscience, Biophysics, or a related field, plus 3+ years of relevant experience
Proficient in electrophysiology techniques (e.g., patch-clamp) and calcium imaging (e.g., Fura-2, GCaMP)
Strong understanding of ion channel function and neuronal signaling pathways, especially in nociceptors
Data Analysis: Familiarity with tools such as MATLAB, Python, Clampfit, and ImageJ
Excellent written and verbal communication skills for preparing research reports and publications and institutional compliance
Preferred
Advanced expertise in ion channel biophysics and electrophysiology
Experience working with rodent model and human primary sensory neurons, in vitro
Familiarity with calcium channels and their role in neuronal function is highly desirable but not required
Strong publication record in relevant fields (e.g., ion channel function in human and rodent nociceptors)
Experience with managing projects and timeline, proactively identify potential research issues and troubleshooting
Able to train junior associates and productively manage project progress
Ability to work independently and as a member of a research team
Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines
Willingness and ability to learn new methods and skills for changing research priorities
Statement of Research (Optional)
Company
University of California, San Francisco
University of California, San Francisco is an educational institution that focuses on medical courses.
H1B Sponsorship
University of California, San Francisco has a track record of offering H1B sponsorships. Please note that this does not
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2023 (313)
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Funding
Current Stage
Late StageTotal Funding
$52.45MKey Investors
California Institute for Regenerative MedicineBaldrick's FoundationNational Institute on Aging
2025-01-30Grant· $11.9M
2023-11-21Grant
2023-10-03Grant
Leadership Team
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