Beam Therapeutics · 2 hours ago
Engineer / Sr Engineer, Manufacturing Sciences & Technology (mRNA/LNP)
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$100K/yr - $135K/yr
6+ years expBeam Therapeutics is a biotechnology company focused on precision genetic medicines. They are seeking a highly motivated Engineer/Senior Engineer to join their Manufacturing Sciences & Technology team, responsible for supporting process technology transfers and GMP manufacturing, collaborating with cross-functional teams, and ensuring compliance with regulatory expectations.
BiotechnologyGeneticsMedicalTherapeutics
Responsibilities
Supports MS&T activities related to mRNA and LNP programs
Supports the technology transfer and implementation of mRNA and LNP GMP manufacturing processes, collaborates with sending and receiving site cross-functional team members
Supports bulk drug substance and bulk drug product manufacturing across the full product lifecycle, including process design, process performance qualification (PPQ), commercial production, and continued process verification (CPV)
Authors technical documentation, including technology transfer plans, facility fit and gap analysis reports, manufacturing study protocols and reports, and risk assessments
Supports equipment design to meet process needs and compliance/regulatory expectations; supports Engineering and Validation departments with subsequent procurement, qualification, and GMP readiness
Supports regulatory submissions, responses, on-site audits, and inspections
Represents MS&T in cross-functional teams related to mRNA/LNP programs and manufacturing operations
Provides person-in-plant (PIP) support in manufacturing at Beam Durham
Supports MS&T lab and non-GMP analytical testing of in-process intermediates, as needed
Establishes trusting and collaborative work relationships across and between Beam sites
Accommodates a flexible schedule during GMP manufacturing, which may include PIP support for critical operations outside of normal business hours
Qualification
Required
Ph.D. in Chemical Engineering, Bioengineering, Biochemistry, or equivalent with minimum 6 years of relevant work experience, or a M.S. degree with a minimum of 8 years of relevant work experience, or a B.S. degree with a minimum 10 years of relevant work experience. Level will be commensurate with experience and academic background
Experience in executing Process Validation lifecycle approach; i.e. process design, PPQ, and CPV
Experience in leading cross-functional teams for non-conformance event investigations, Root Cause Analyses (RCAs), and CAPAs
Outstanding written, verbal, and presentation skills; ability to communicate strategies, plans, and results to a diverse audience
Ability to simultaneously manage multiple projects and priorities and adjust quickly to dynamic situations
High degree of customer focus and collaboration in a team environment
Preferred
Demonstrated experience in technology transfer, scale-up, and implementation of downstream unit operations, such as, tangential flow filtration, normal flow filtration, and chromatography; direct experience in downstream process development is preferred
Experience with DLS, UV spectroscopy, and UPLC/HPLC analytical testing methods is a plus
Company
Beam Therapeutics
Beam Therapeutics is a biotechnology company developing precision genetic medicines through the use of base editing technology.
501-1000 employees
H1B Sponsorship
Beam Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (9)
2024 (9)
2023 (12)
2022 (9)
2021 (7)
2020 (4)
Funding
Current Stage
Public CompanyTotal Funding
$1.19B2025-03-10Post Ipo Equity· $500M
2021-01-19Post Ipo Equity· $260M
2020-02-11Post Ipo Equity· $207M
Leadership Team
John Evans
CEO
Christine Bellon
Chief Legal Officer
Recent News
2025-12-16
2025-12-09
Company data provided by crunchbase