Scripps Research · 2 weeks ago
RESEARCH ASSISTANT IV - Molecular Biology and Protein Engineering
San Diego, CA
Full-time
Onsite
Mid, Senior Level
$75K/yr - $94K/yr
5+ years expScripps Research is a nonprofit translational research institute dedicated to creating the next generation of medicines. They are seeking a Research Assistant IV to join their molecular biology and protein engineering team, where the successful candidate will collaborate with scientists to produce proteins, plasmids, and viral vectors for innovative R&D programs.
BiopharmaBiotechnologyMedical
Responsibilities
Design and clone genes into vectors for mammalian, coli, insect, or yeast expression
Protein expression primarily in mammalian cells, sometimes in coli, insect cells, or yeast
Protein purification by affinity chromatography, gel-filtration, and other chromatography techniques (ion exchange, hydrophobic interaction chromatography, etc.)
Protein characterization by SDS-PAGE, analytical SEC-HPLC, LCMS, biolayer interferometry (BLI) and other methods
Documentation of plasmids and proteins in the database
Presentation of results in group meetings and communication with team members
Qualification
Required
Bachelor's degree with 7+ years' experience, or master's degree with 5+ years' experience in protein chemistry, chemical biology, biochemistry, or relevant scientific discipline
Molecular biology techniques, including construct design, DNA isolation and purification, and assembly-based cloning are required
Protein expression in HEK, CHO, or E. coli, is required
Protein purification techniques are required, including a basic understanding of FPLC, HPLC, gravity drip columns, and a range of affinity and capture technologies including SEC, IEX, mixed-mode, etc
An understanding of biophysical characterization of proteins is important
Outstanding organizational skills and experience in preparing scientific and technical documents are important
Demonstrated excellence in designing and conducting hands-on experiments, organizing and managing projects, and maintaining meticulous documentation
Highly motivated and creative with a devotion to project goals and timelines
Proficient in collaborating and communicating effectively with colleagues and management teams
Ability to meaningfully contribute to scientific discourse
Preferred
Experience with yeast and insect expression platforms is advantageous
Medium- and high-throughput protein expression is not required but advantageous
While prior industry experience is preferred, outstanding candidates without this will be considered
Benefits
Employer Contributed Retirement Plan – Depending on eligibility, employees receive an employer contributed retirement plan (no employee contribution required) and the option to contribute to a 403(b) (which is similar to a 401(k) using your own pre or post-tax dollars)
Full Suite of Health and Welfare plans including three medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more
Access to Flexible Spending Accounts (Medical/Dependent Care)
Competitive vacation and sick leave policies
Free, on-site parking
Company
Scripps Research
Scripps Research is a leader in the discovery and application of biomedical breakthroughs that improve human health.
1001-5000 employees
H1B Sponsorship
Scripps Research has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2020 (1)
Funding
Current Stage
Late StageTotal Funding
$71.2MKey Investors
National Institute of Diabetes and Digestive and Kidney DiseasesThe Conrad Prebys FoundationNational Institute of Allergy and Infectious Diseases
2025-10-08Grant· $3.2M
2025-05-28Grant· $1M
2022-05-18Grant· $67M
Leadership Team
Ed Ramos
Director of Digital Clinical Trials, Co-founder Digital Trials Center
Caroline M.
Chief Operating Officer
Recent News
2026-01-16
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