Scientist II, In Vivo, Enzymatic and Metabolic Therapeutic Area jobs in United States
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BioMarin Pharmaceutical Inc. · 3 weeks ago

Scientist II, In Vivo, Enzymatic and Metabolic Therapeutic Area

BioMarin Pharmaceutical Inc. is a global biotechnology company focused on developing transformative medicines for genetic conditions. They are seeking a motivated Scientist to join the Enzymatic and Metabolic In Vivo team to design and execute key in vivo studies aimed at developing therapeutics for genetic metabolic disorders.

BiotechnologyDeveloper PlatformPharmaceutical
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Conduct research on genetic metabolic diseases
Contribute to novel therapeutic programs based on innovative, ground-breaking discoveries that could lead to new, high-impact opportunities for patients
Perform research and publish findings in high-impact journals and present research at major conferences
Effectively partner with other scientists and the Research and Early Development team to develop and execute on the program's strategic plan
Present program data at a range of internal forums, including project team meetings, Research Department Seminars and Research leadership governance forums
Write, review and contribute to study synopses, protocols, study reports and regulatory documents
Collaborate with various BioMarin functions, CROs, university or analytical laboratories, business partners, as necessary to ensure appropriate/timely progression of projects
Participate in multi-disciplinary drug development teams and may lead sub-teams
Excellent written and verbal communication
Ability to build/foster productive cross-functional collaborations both within and external to BioMarin
Execute hands-on responsibilities including but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. In addition, providing daily care and monitoring of mice or rats, including health checks and documentation, will also be required
Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation
Communicate experimental plans and results to the project team. Support product development and regulatory filings for pivotal clinical studies
Follow instructions and work independently to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines
Share your knowledge and understanding with other team members
Document experimental methods and outcomes using Electronic Lab Notebooks and generation/maintenance of technical procedure documents and SOPs
Other duties as assigned
Willingness to work on site full time including off hours and weekends based on study needs
Other duties as assigned

Qualification

Vivo researchMetabolic disease expertiseAnimal model developmentDosing techniquesIVIS imagingAnalytical skillsData managementWritten communicationCollaboration skillsProblem-solving skills

Required

Demonstrated experience in metabolic biology/disease research in academia or industry (preferred) including publication record
Strong analytical, problem-solving, and decision-making skills
Strong understanding of genetically engineered models, breeding, and management and Gene therapy modalities
Excellent oral and written communication skills
Passion for contributing your scientific skills to develop therapies for patients in need
Must be able to utilize computer databases for analysis, data entry, and point of care observations
Must be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams
Must be able to work with external regulatory agencies and accreditation groups
Some 'off-core business hours' work required
Complete all company training requirement
Perform all work per designated safety standards and comply with Personal Protective Equipment requirements and occupational health to perform work tasks
This position is an on-site critical required position
PhD in a related subject area with demonstrated in vivo research experience in metabolic disease
Extensive hands-on experience with rodent in vivo work in the metabolic field

Preferred

Postdoctoral or industry (2-5 years preferred) experience in genetic metabolic diseases

Benefits

Discretionary annual bonus
Discretionary stock-based long-term incentives
Paid time off
Company-sponsored medical, dental, vision, and life insurance plans

Company

BioMarin Pharmaceutical Inc.

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Founded in 1997, BioMarin is a global biotechnology company dedicated to transforming lives through genetic discovery.

H1B Sponsorship

BioMarin Pharmaceutical Inc. has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (34)
2024 (23)
2023 (24)
2022 (26)
2021 (24)
2020 (19)

Funding

Current Stage
Public Company
Total Funding
$585.8M
2020-05-11Post Ipo Debt· $585.8M
1999-07-26IPO

Leadership Team

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Brian Mueller
Chief Financial Officer
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Arpit Davé
Executive Vice President, Chief Digital and Information Officer
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Company data provided by crunchbase