Anvia Therapeutics · 2 days ago
Scientist II, Immunology
New York, NY
Full-time
Onsite
Entry, Mid Level
$115K/yr - $150K/yr
2+ years expAnvia Therapeutics is a dynamic and innovative biotech company dedicated to developing small molecule inhibitors for inflammatory and autoimmune diseases. The role involves driving hypothesis-driven in vitro immunology research and executing complex cellular assay systems to support immune pharmacology and mechanism-of-action studies across various inflammatory disease programs.
Biotechnology
Responsibilities
Design and execute hypothesis-driven cellular assays to support immune pharmacology, target validation, and MoA studies
Develop, optimize, and validate complex in vitro assay systems using primary immune cells, patient-derived samples, and disease-relevant or engineered cell lines
Perform functional immune assays including cell activation, proliferation, cytokine production, signaling, and cytotoxicity, using both primary and cell-line–based systems
Contribute to immune pharmacology assessments, including compound potency, pathway modulation, selectivity, and translational relevance
Apply a strong mechanistic understanding of immune and inflammatory signaling pathways to guide assay design and data interpretation
Utilize flow cytometry, ELISA/MSD/other cytokine/chemokine profiling techniques, protein- and signaling-based assays, and related techniques to generate high-quality, reproducible data
Analyze, interpret, and clearly communicate experimental results to project and leadership teams
Troubleshoot and refine experimental systems to improve robustness, scalability, and biological relevance
Maintain accurate experimental records using electronic laboratory notebooks
Collaborate closely with lead discovery, chemistry, translational, and external partners to advance program milestones
Stay current with emerging immunology technologies and incorporate innovative methodologies where appropriate
Qualification
Required
PhD in Immunology, Biology, Biotechnology, Molecular Biology, or a related field with 2+ years of relevant experience
Hands-on experience developing and executing complex cellular assays using primary immune cells, patient-derived samples, and cell line–based systems
Experience working with functional immune readouts, including flow cytometry–based phenotyping and signaling assays, and cytokine measurement (ELISA/MSD/other)
Demonstrated expertise in protein-level analysis of signaling pathways, including Western blotting and related biochemical techniques used to assess pathway activation, inhibition, and mechanism of action
Strong understanding of cell signaling pathways relevant to immune and inflammatory biology
Proven ability to independently design experiments, troubleshoot assays, and manage multiple priorities
Proficiency with data analysis and visualization tools (e.g., GraphPad Prism, FlowJo, Excel)
Excellent written and verbal communication skills
Preferred
Experience supporting immune pharmacology and MoA characterization in early drug discovery
Background in inflammatory or autoimmune disease biology (IBD, RA, dermatology preferred)
Familiarity with assay validation, quantitative potency assessment and translational biomarker analysis/ identification
Experience working in a fast-paced, innovative biotech environment
Benefits
Health insurance
Paid time off
Retirement plan options
Company
Anvia Therapeutics
Anvia Therapeutics is developing small molecule inhibitors against clinically validated targets to expand treatment options for patients suffering from inflammatory and autoimmune diseases.
2-10 employees
Funding
Current Stage
Early StageCompany data provided by crunchbase