St. Jude Children's Research Hospital · 1 week ago
Postdoctoral Research Associate in Gorgulla Lab
Memphis, TN
Full-time
Onsite
Senior Level
$72K/yr - $72K/yrSt. Jude Children's Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The postdoctoral research associate will advance computational drug discovery by developing deep learning-based methods to identify novel small-molecule therapeutics and collaborate with scientists to translate computational predictions into testable hypotheses.
BiotechnologyCharityHealth CareHealth DiagnosticsHospitalMedicalNon Profit
Responsibilities
Design and execute computational screening campaigns to identify and prioritize candidate small molecules for experimental validation, with a focus on developing generalizable workflows and tools
Develop or refinement methodologies that improve hit identification, pose prediction, or scoring accuracy, and apply them in drug discovery projects
Collaborate closely with other scientists within the lab and with external academic or industrial partners to translate computational predictions into testable hypotheses
Mentor graduate students or interns in computational techniques, reproducible workflows, and best practices in data-driven discovery
Contribute to manuscript preparation, grant proposals, and presentations, with opportunities to co-lead sections related to methods or results
Participate in professional development activities, including conference attendance, skill-building workshops, or cross-disciplinary training
Qualification
Required
A Ph.D. in computational chemistry, structural biology, bioinformatics, computer science, pharmaceutical sciences, or a closely related field
Very strong background and skills in deep learning and machine learning
Machine learning frameworks, in particular PyTorch
Experience in drug discovery or ability to adapt quickly to applied domains such as drug discovery
Proficiency in programming or scripting (e.g., Python, Bash, or similar) for workflow automation and data analysis
Ability to think critically about experimental data and translate findings into actionable research directions
Excellent communication skills, both written and verbal, with the ability to present findings clearly to collaborators from diverse scientific backgrounds
Self-motivated, organized, able to contribute to a team-oriented environment
Preferred
Computational molecular modeling, computational biology, computational drug discovery, cheminformatics, and/or quantum chemistry
Cuda, TensorFlow
Familiarity with common tools for structure-based molecular modeling or virtual
Experience developing or benchmarking computational methods for drug discovery, scoring functions, predictive models or quantum chemistry
Machine learning or AI frameworks applied to molecular discovery
Familiarity with cloud or high-performance computing environments
Experience collaborating with experimental scientists or participating in multidisciplinary projects
Prior mentorship of students or involvement in team-based problem solving
Interest in contributing to manuscripts, grant proposals, or open-source software
Benefits
Comprehensive benefits
Generous relocation assistance
Access to grant writing workshops
Individual development plans
Teaching and mentoring opportunities
Non-research career advancement programs
Professional development allowance
Company
St. Jude Children's Research Hospital
St.
Founded in 1962
5001-10000 employees
H1B Sponsorship
St. Jude Children's Research Hospital has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (370)
2024 (316)
2023 (309)
2022 (255)
2021 (251)
2020 (201)
Funding
Current Stage
Late StageTotal Funding
$62.4MKey Investors
Kia MotorsKBR Charity Golf TournamentHyundai Hope On Wheels
2025-05-12Grant· $1.5M
2024-10-28Grant
2024-08-28Grant· $0.4M
Leadership Team
Judy A. Habib
Chair, Board of Directors
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