Tonix Pharmaceuticals · 1 month ago
Director, AI Discovery
Berkeley Heights, NJ
Full-time
Onsite
Director/Executive
$150K/yr - $240K/yr
20+ years expTonix Pharmaceuticals is a fully integrated biotechnology company focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. The Director of AI Discovery will lead the strategic development and application of artificial intelligence and computer-aided drug design to accelerate research and development, collaborating with various experts to advance Tonix's pipeline in CNS, rare disease, immunology, and infectious disease.
BiopharmaBiotechnologyMedicalPharmaceutical
Responsibilities
Define and implement Tonix's computational and AI-driven drug discovery strategy in alignment with company R&D priorities
Lead computational and AI-enabled design initiatives to accelerate drug discovery and development
Develop and apply AI/CADD-based approaches to target validation, hit-to-lead optimization, ADME/Tox profiling, and preclinical safety and efficacy assessment
Develop and integrate scalable AI/ML tools, data workflows, and high-performance computing solutions to support Tonix's discovery pipeline
Collaborate closely with chemists, biologists, pharmacologists, and informatics experts to translate computational insights into actionable experimental hypotheses
Contribute to publications, patents, and presentations that enhance Tonix's scientific visibility in AI-enabled drug discovery
Qualification
Required
Ph.D. in Pharmacology, Chemistry, Structural Biology, or a related discipline
20 years of experience in drug design and discovery, including leadership in developing and applying AI/CADD approaches to advance programs from concept to clinical stage
Ligand-based drug design expertise: AI/ML, QSAR, neural networks, pharmacophore modeling, de novo design, virtual screening, and ADME/Tox modeling
Structure-based drug design expertise: sequence analysis, protein modeling, molecular docking, AlphaFold, molecular dynamics simulations, and free energy perturbation
Proficiency with modern molecular modeling platforms, such as Schrödinger, MOE, AlphaFold, and AMBER
Experienced in AI/ML programming and data analysis, such as Python (Jupyter Notebook, Chemprop, RDKit, Scikit-learn, NumPy, Pandas) and bash scripting
Strong understanding of CNS, pain biology, and translational pharmacology
Demonstrated ability to collaborate effectively in multidisciplinary settings and to communicate complex modeling results to non-specialist teams
Experience managing collaborations with external chemistry partners and CROs
Proven leadership, project management, and mentorship capabilities
Benefits
Medical, Dental & Vision Insurance
Basic and Voluntary Life and AD&D Insurance
Short- and Long-Term Disability Insurance
Flexible Spending Accounts
Health Savings Account
Employee Assistance Programs
Pet Insurance
Retirement Savings 401k with company match and annual discretionary stock options
Generous Paid Time Off
Sick Time
Paid Holidays
Career Development and Training
Company
Tonix Pharmaceuticals
Tonix is a biopharmaceutical company, publicly traded on NASDAQ (ticker: TNXP).
51-200 employees
H1B Sponsorship
Tonix Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2022 (1)
Funding
Current Stage
Public CompanyTotal Funding
$336.74MKey Investors
Point72Medical CBRN Defense ConsortiumTechnology Partners
2025-12-29Post Ipo Equity· $20M
2025-03-10Grant
2024-06-12Post Ipo Equity· $4M
Leadership Team
Seth Lederman
CEO
Zeil Rosenberg
Executive Vice President, Medical
Recent News
2025-12-29
2025-12-29
Company data provided by crunchbase