Astellas Pharma · 1 week ago
Scientist II, BioConjugation, Antibody Drug Conjugate
South San Francisco, CA
Full-time
Onsite
Entry, Mid Level
$104K/yr - $163K/yr
2+ years expAstellas Pharma is a pharmaceutical company committed to innovative science and medical solutions. They are seeking a Scientist II to focus on bioconjugation for Antibody-Drug Conjugates, primarily working on conjugation and purification processes to support research activities.
BiotechnologyHealth CareMedical
Responsibilities
Perform conjugation and purification to prepare ADCs to support research activities
Design, optimize and develop CMC friendly conjugation process
Lead the creation of optimal ADC clinical candidates by appropriate conjugation methods
Manage CROs to perform above activities
Actively participate in ADC projects, contributing to team decision-making through the creation of ADCs and the data you generate
Serve as an ADC Subject Matter Expert (SME), offering appropriate advice and solutions
Contribute to patents, publications, and technical reports
Qualification
Required
PhD with 2+ years relevant laboratory experience in biologics research
Extensive hands-on experience with a wide range of conjugation chemistry, including but not limited to lysine, cysteine, and enzymatic mediated conjugation methods
Experience in analytical methods for protein characterization, ideally antibody related modalities
Desire and ability to work in cross-functional, flexible and team-oriented environment
CRO management experience
Well-balanced communication skills (active & passive) in own language and in English
Preferred
Experience in antibody-related modality development especially in antibody-drug conjugates (ADCs)
Experience supporting ADC development from discovery to early CMC development
Experience in oncology research
Experience in patent application
Experience in collaborations with external research groups
Benefits
Medical, Dental and Vision Insurance
Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
401(k) match and annual company contribution
Company paid life insurance
Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
Long Term Incentive Plan for eligible positions
Company-paid fleet vehicle for eligible positions
Referral bonus program
Company
Astellas Pharma
Astellas Pharma is a global pharmaceutical research & development company.
10001+ employees
H1B Sponsorship
Astellas Pharma has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (7)
2024 (4)
2023 (4)
2022 (2)
2021 (3)
2020 (5)
Funding
Current Stage
Public CompanyTotal Funding
unknownKey Investors
National Institute on Drug Abuse (NIDA)
2020-07-22Grant
2008-10-13IPO
Leadership Team
Amanda Hart
Head, Global Commercial Analytics and Reporting
Recent News
2026-01-07
Company data provided by crunchbase