GenEdit · 1 month ago
Scientist I, Immunology
South San Francisco, CA
Full-time
Onsite
Entry Level
1+ years expGenEdit is a rapidly-growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. They are seeking a talented and motivated Scientist to join their Immunology team and drive the development of genetic medicines for immune-based diseases utilizing hydrophilic nanoparticle technology.
BiotechnologyGeneticsPharmaceuticalTherapeutics
Responsibilities
Lab: Conceptualize and execute complex in vitro and in vivo immunology studies including study design, method development, independent data analysis, and technical problem solving. (75% bench work)
Scientific leadership: Assist in goal setting and strategy, project and study planning, resource management, mentorship of junior staff, and hands-on study execution to ensure timely achievement of corporate milestones and goals. Function internally as a key opinion leader in matters related to immunology and tolerance
Supervisor: May manage Research Associate(s) depending on experience including: workflow organization, goal setting, assigning objectives, mentoring, performance evaluation, skills and career development
Collaboration and communication: Work cooperatively with peers and multidisciplinary teams in a highly matrixed lab environment, keep detailed and organized lab records, and present results at team, internal company, and external alliance meetings
Qualification
Required
Ph.D or equivalent in Immunology or a related life science field
1-2 years of biotech/pharma experience
Broad and deep knowledge in immune response regulation and modulation at the cellular and molecular level
Direct experience in development, troubleshooting, and execution of in vitro immune based assays including primary immune cell culture and differentiation, immune cell phenotyping, and functional assays (e.g., flow cytometry, ELIspot, cytotoxic T cell assays, APC/T cell co-culture)
Deep understanding of the antigen presentation process, Treg, DC and/or macrophage biology, and immune modulation
Work authorization in the US is required
Primary immune cell culture of DC, monocyte, macrophage, and T cells including in vitro and ex vivo functional assays
Design and execution of in vivo studies to evaluate therapeutic drug candidates for safety and efficacy in mouse models of autoimmune and inflammatory diseases
Proficiency with comprehensive immune cell phenotyping by multicolor (12+) flow cytometry (Cytek Northern Lights, BD cytometers, CytoFlex), ICC (Cytation), cytokine analyses (CBA, MSD), ELISA, ELISpot, and ICS, and related assays
In vitro and in vivo screening of drug candidates, microplate cell assays, protein expression, cytotoxicity, fluorescent cell and tissue imaging, luminescence, BLI (IVIS), quantitative microscopy and image analysis
A highly professional, enthusiastic, self-starting and goal-focused scientist
Intellectually agile, curious, and able to thrive in a fast-paced, dynamic environment
Excels at technical innovation and creative problem solving, prevention and solution
Open-minded, cooperative, and capable of adapting quickly
Experience working collaboratively across functional groups and with external partners
Personable, sociable, and eager to help build Genedit's culture and future
Preferred
Relevant postdoctoral experience in immune tolerance and autoimmune diseases
Knowledge of tolerance, vaccine development and gene therapy/delivery
Preferred experience with molecular biology techniques including characterization of nucleic acid and protein therapeutic payloads
Company
GenEdit
GenEdit develops next generation therapeutics for genetic diseases through safe and efficient CRISPR/Cas9 delivery.
11-50 employees
H1B Sponsorship
GenEdit has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (1)
Funding
Current Stage
Early StageTotal Funding
$67.72MKey Investors
Qiming Venture PartnersEli LillyNational Science Foundation
2024-01-23Series A· $24M
2021-11-01Angel· $9M
2021-09-23Series A· $26M
Leadership Team
Hyo Min Park
Co-Founder & Chief Operating Officer
Timothy Fong
Chief Technology Officer
Recent News
2024-05-05
Company data provided by crunchbase