Scientist I, Medicinal Chemistry jobs in United States
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Maze Therapeutics · 4 days ago

Scientist I, Medicinal Chemistry

positionSouth San Francisco, CA
timeFull-time
remoteOnsite
seniorityMid, Senior Level
money$134K/yr - $163K/yr
date5+ years exp

Maze Therapeutics is a clinical-stage biopharmaceutical company focused on developing precision medicines using human genetics. The Scientist I in Medicinal Chemistry will design and synthesize novel molecules, collaborate across disciplines, and contribute to drug discovery programs.

BiopharmaBiotechnologyGeneticsTherapeutics
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H1B Sponsor Likelynote

Responsibilities

Design and synthesize novel chemical entities aligned with project goals
Conduct multistep syntheses of complex small molecules and characterize intermediates and final products
Collaborate with chemists, biologists, and external partners to optimize pharmacological properties
Contribute to patents, reports, and scientific publications
Present project results and strategy in key company meetings
Mentor junior colleagues and troubleshoot synthetic challenges using literature and best practices

Qualification

Synthetic organic chemistryChemical synthesisMedicinal chemistry conceptsCollaboration skillsCommunication skills

Required

Ph.D. in synthetic organic chemistry or related discipline, or M.S. with 5+ years industry experience, or B.S. with 10+ years industry experience
Proven expertise in chemical synthesis (publications or industry achievements)
Strong collaboration skills and a proactive, solution-oriented approach
Familiarity with medicinal chemistry concepts and ability to learn quickly
Enthusiasm for applying chemistry to solve complex challenges at the intersection of genetics, functional genomics, and biology
Excellent communication skills and attention to detail

Benefits

Competitive medical, dental, and vision insurance
Mental health offerings
Equity incentive plan
401(k) program with employer match
Generous holiday and PTO policy

Company

Maze Therapeutics

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Maze Therapeutics is a biotechnology company that develops precision medicines for renal, cardiovascular, and metabolic diseases.
dateFounded in 2017
location
South San Francisco, California, USA
people-size51-200 employees
web-link
https://www.mazetx.com

H1B Sponsorship

Maze Therapeutics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (3)
2023 (2)
2022 (5)
2021 (3)
2020 (1)

Funding

Current Stage
Public Company
Total Funding
$646M
Key Investors
Matrix Capital ManagementCity Hill Ventures
2025-09-11Post Ipo Equity· $150M
2025-01-31IPO
2024-12-03Series D· $115M

Leadership Team

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Jason Coloma
Chief Executive Officer
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Misbah Tahir
Chief Financial Officer
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Recent News

BioSpace
IPOs Slow to a Trickle in 2025 as Investors Grow More Discerning
2026-01-06
Maze Therapeutics, Inc.
Maze Therapeutics Reports Third Quarter 2025 Financial Results and Recent Highlights
2025-11-09
StreetInsider.com
Maze Therapeutics presents drug data at kidney conference
2025-11-07
Company data provided by crunchbase