Genentech · 9 hours ago
Principal Mechanical Engineer Project Manager
South San Francisco, CA
Full-time
Onsite
Lead/Staff
15+ years expGenentech is establishing a new Campus Development Team to oversee the implementation of the Campus Vision Plan for the South San Francisco campus. The Senior Principal Mechanical Engineer will provide accountability for the successful delivery of mechanical systems in laboratory and research environments, ensuring they meet the highest standards of quality and safety. This role involves technical leadership, project planning, and coordination with various stakeholders to support innovative laboratory designs.
BiotechnologyLife ScienceManufacturing
Responsibilities
Provides technical leadership and deep subject matter expertise for the mechanical engineering designs supporting gRED research laboratories, specialized vivarium spaces, and associated supporting projects
Actively leads the design and planning of HVAC, plumbing, fire protection, building controls, automation and energy management critical to laboratory operations and specialized vivarium environments
Coordinates with the Utility Master Plans to ensure that upgrades to critical mechanical infrastructure (including the Regional Utility Plant and Electrical Distribution Hub) directly support the reliability, redundancy and scalability required by the new lab facilities
Serves as a respected industry expert on laboratory mechanical design, engaging with the Roche/Genentech internal and industry external network to learn, influence, and collaborate on new technologies and best practices for gRED
Primary focus will be ensuring scientific user requirements are incorporated into robust technical solutions for the gRED project
Provide expert design guidance on HVAC, plumbing, fire protection, building controls, automation and energy management to labs and strategies for flexible 'plug-and-play' capabilities, and robust back-up systems to protect critical experiments, data, and animal life-support systems
Work closely with other technical leads to ensure seamless integration of HVAC, plumbing, fire protection, building controls, automation and energy management systems with lab-specific platforms like Building Automation Systems (BAS) and environmental monitoring systems
Serve as the mechanical SME in all design and user-group meetings, providing clear technical options analysis and advocating for designs that prioritize scientific workflow, flexibility, and safety
A key function of this role will also be to ensure all mechanical designs align with Roche/Genentech and site-specific standards, with a particular focus on standards governing laboratory design and vivarium operations
Coordinates the mechanical scope into a comprehensive strategy to address the technical needs across all aspects of the gRED project, from main infrastructure to the point-of-use in the lab
A portion of the Principal Mechanical Engineer’s time will be spent supporting broad Design Engineering & Construction Services process improvement projects and LEAN initiatives, applying these principles to improve the lab design and delivery process
The Senior Principal Mechanical Engineer will be responsible for driving innovation in mechanical systems specifically for R&D environments, adopting technologies that improve lab flexibility, energy efficiency, and operational reliability
This role will participate in the development of a project-wide mechanical infrastructure strategy, in partnership with the Design team, to ensure the new gRED labs are adaptable for future scientific platforms and technologies, reducing total cost of ownership while maximizing uptime and research continuity
A key portion of the role is continuous learning, engagement with the Roche engineering network (technical experts within the Roche Global organization and other Roche sites) as well as outside industry organizations, including ASHRAE, ISPE and others
Project Planning and Coordination: Develop and maintain a comprehensive project plan, coordinating with architects, engineers, and contractors. Apply innovative thinking to proactively identify and mitigate risks, while monitoring progress via KPIs and reporting status to senior management
Budgeting and Resource Management: Support the development and management of the project budget, ensuring cost control and effective resource allocation. This role also supports all procurement activities, including vendor selection, contract negotiation, and material acquisitions
Stakeholder Management: Build and maintain strong relationships with internal and external stakeholders, fostering collaboration, transparency, and alignment. Serve as a trusted liaison, keeping all parties informed and engaged through regular meetings and progress reports
Team Leadership: Provide effective leadership by clarifying roles and fostering a collaborative, motivated work environment. Mentor and guide team members while also contributing strategic design and technical expertise to the facility's construction
Quality Control: Implement and enforce strict quality control measures to ensure compliance with industry standards and specifications
Qualification
Required
Bachelor's degree in Mechanical Engineering or equivalent
15 years or more pharmaceutical technology experience in industry or academia after receiving their Bachelor's Degree, at least 8 of which involved mechanical system design, construction and/or commissioning and qualification activities
Working knowledge of ANSI / ASHRAE, NEMA, NFPA, EPA, and OSHA standards as well as relevant chemical industry specific standards and documentation (piping and instrumentation diagrams, process flow diagrams)
Must have excellent communication (written/verbal), presentation, leadership, interpersonal, collaborative, conflict resolution, and negotiating skills
Excellent organization and planning skills
Advanced Microsoft Office and Google Suite skills
Exceptional teamwork and collaboration skills are essential to facilitate the work of cross-functional and interdepartmental teams
Must be dependable, provide attention to details, and execute proficiently in coordination tasks
Self-starter and ability to work with minimum or no supervision
Preferred
Pharmaceutical GMP project mechanical design experience
LEED certification
Experience in project management
LEAN / Six Sigma certification
Experience working in a campus environment
Benefits
A discretionary annual bonus may be available based on individual and Company performance.
This position also qualifies for the benefits detailed at the link provided below.
Company
Genentech
Genentech is a biotechnology research company that specializes in genetic testing and personalized medicines.
10001+ employees
H1B Sponsorship
Genentech has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (167)
2024 (148)
2023 (150)
2022 (178)
2021 (121)
2020 (158)
Funding
Current Stage
Public CompanyTotal Funding
unknown2009-03-26Acquired
1999-07-20IPO
1976-01-01Series Unknown
Leadership Team
Ashley Magargee
CEO
Michael Laird
Vice President
Recent News
2025-12-30
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2025-12-24
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