Lyell Immunopharma · 1 month ago
Senior Director, Medical Affairs, Solid Tumors
California, United States
Full-time
Onsite
Director/Executive
$250K/yr - $300K/yr
8+ years expLyell Immunopharma is a clinical-stage company focused on advancing next-generation CAR T-cell therapies for solid tumors and hematologic malignancies. The Senior Director, Medical Affairs – Solid Tumors will lead the medical affairs strategy for solid tumor programs, ensuring scientific excellence and establishing partnerships with external stakeholders in the oncology space.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Serve as Lyell’s Medical Affairs lead for mCRC and future solid tumor programs, providing deep disease-area expertise and independent strategic direction
Partner closely with the SVP, Medical Affairs and the VP, Medical Affairs to shape and evolve the overall vision for Medical Affairs
Lead the development and execution of S. Medical Affairs strategy for solid tumors, aligned with corporate, clinical, and regulatory objectives
Shape medical narrative, scientific platform, core claims, and evidence-generation needs to support evolving program priorities
Drive Medical Affairs contributions to launch readiness for solid tumor assets
Build and maintain strong professional relationships with Key Opinion Leaders (KOLs), investigators, and academic centers, specifically within the GI oncology and solid tumor communities
Represent Lyell at key scientific congresses (e.g., ASCO, ESMO, GI ASCO) and advisory boards to facilitate scientific exchange
Gather and synthesize external insights to shape Medical Affairs initiatives and support clinical development priorities
Oversee the development of medical narratives, scientific platforms, and publications strategy for the solid tumor portfolio
Ensure compliant, high-quality execution of medical communication initiatives and educational materials relevant to the colorectal cancer program
Provide scientific training and guidance to internal teams and field medical staff to ensure consistency and accuracy of scientific messaging
Demonstrate independent leadership in managing projects, resources, and potential direct reports or cross-functional teams to meet program deliverables
Ensure all Medical Affairs activities within the solid tumor program comply with legal, regulatory, and corporate standards
Contribute to the development of governance frameworks and authorship policies as a senior member of the Medical Affairs team
Qualification
Required
MD, DO, PharmD, or PhD required
Minimum 8–10 years of pharmaceutical/biotech industry experience, with 5+ years in Medical Affairs
Extensive experience in oncology is required; prior experience in metastatic colorectal cancer, cell therapy, or immuno-oncology is highly desirable
Proven track record of independently leading medical strategy for a specific asset or therapeutic area
Strong knowledge of U.S. compliance and regulatory requirements applicable to Medical Affairs
Strong scientific expertise in oncology, with the ability to analyze, interpret, and communicate complex scientific data
Exceptional interpersonal and communication skills; comfortable engaging with external experts and internal senior leaders
Strong strategic acumen and ability to drive multiple concurrent initiatives
Demonstrated leadership without formal authority; ability to mentor future Medical Affairs team members
Ability to operate effectively in a fast-paced, high-growth biotech environment with limited infrastructure
Ability to effectively collaborate with and influence cross-functional stakeholders at senior levels
Preferred
Oncology specialty required; specific background in GI oncology or solid tumors strongly preferred
Launch experience is strongly preferred
Benefits
Subsidized medical, dental and vision plans from your first day of employment
FSA
Company provided Life and AD&D Insurance
STD and LTD Insurance
ESPP
401(k) Plan with Company match
Mass transit commuter benefits
Cell phone reimbursement
A range of supplemental benefits that you may choose to elect
18 days’ vacation
9 day’s sick leave
8 observed holidays
A floating holiday
Summer and a winter office shutdown
Company
Lyell Immunopharma
Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer.
201-500 employees
H1B Sponsorship
Lyell Immunopharma has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (2)
2023 (2)
2022 (5)
2021 (2)
2020 (3)
Funding
Current Stage
Public CompanyTotal Funding
$543M2025-07-25Post Ipo Equity· $50M
2021-06-16IPO
2020-03-12Series C· $493M
Leadership Team
Lynn Seely
President & Chief Executive Officer
V
Veronica Bulis
Vice President and Corporate Controller
Recent News
2025-12-25
2025-12-19
2025-12-09
Company data provided by crunchbase