Madrigal Pharmaceuticals · 1 day ago
Senior Manager, AI and Data Science
Conshohocken, PA
Full-time
Hybrid
Senior Level
$163K/yr - $200K/yr
7+ years expMadrigal Pharmaceuticals is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH). They are seeking a Senior Manager, AI and Data Science to lead the development of advanced AI solutions and enhance decision quality across the organization.
BiopharmaBiotechnologyMedical DevicePharmaceutical
Responsibilities
Lead end-to-end development of machine learning and AI models, from problem framing through deployment and ongoing evaluation
Collaborate effectively with data scientists, ML engineers, and cross-functional partners to design and deliver AI solutions that support business and scientific needs
Work with stakeholders to identify high-value opportunities for AI that enhance Commercial, Medical, and enterprise-level processes
Build and optimize AI agents and orchestration workflows using modern agentic frameworks such as LangGraph, LlamaIndex, or CrewAI
Develop modular and reusable components for reasoning, retrieval, tool integration, and workflow automation
Develop end-to-end agentic frameworks incorporating agent connectors, MCP tools, and integrated interfaces, working closely with the Agentic UI team to ensure seamless product delivery
Design and deploy machine learning models, including applications in recommendation, personalization, and other ML-driven decision-support systems
Apply modern ML techniques, including embeddings, graph methods, and generative model integration to real-world healthcare and Commercial challenges
Build AI solutions for Commercial use cases in Healthcare and Life Sciences
Partner with data engineering teams to ensure scalable, ML-ready data pipelines and model monitoring
Utilize platforms such as Databricks to support model development, optimization, and operationalization
Translate complex AI concepts into clear, actionable insights for technical and non-technical partners
Align AI initiatives with enterprise governance, privacy, and compliance expectations
Qualification
Required
Master's or Ph.D. in Computer Science, Data Science, Engineering, Statistics, or related field
7+ years of experience in data science and applied machine learning
3+ years implementing and deploying machine learning or AI systems in production environments
1+ year of hands-on agentic AI development using frameworks such as LangGraph, LlamaIndex, or CrewAI
Experience working with patient-level data and feature engineering
Experience building recommender systems or related ML approaches
Proficiency in Python, ML frameworks (PyTorch, Scikit-learn, MLflow), and data tools (Spark, SQL)
Demonstrated ability to work collaboratively across scientific, technical, and business teams
Strong communication skills with the ability to convey complex concepts clearly
Experience in Healthcare or Life Sciences
Preferred
Familiarity with Databricks and modern cloud-based ML development
Experience deploying Agents to production environments
Proven track record of building AI solutions in Healthcare and Life Sciences
Benefits
Flexible paid time off
Medical, dental, vision and life/disability insurance
401(k) offerings (i.e., traditional, Roth, and employer match)
Supplemental life insurance
Legal services
Mental health benefits through our Employee Assistance Program for employees and their family
Company
Madrigal Pharmaceuticals
Madrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases.
501-1000 employees
H1B Sponsorship
Madrigal Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.94BKey Investors
Blue OwlHercules Capital
2025-07-22Post Ipo Debt· $350M
2024-03-18Post Ipo Equity· $690M
2023-09-28Post Ipo Equity· $500M
Leadership Team
Mardi C. Dier
Chief Financial Officer
Carole Huntsman
Chief Commercial Officer (CCO)
Recent News
2025-12-10
2025-11-13
2025-11-11
Company data provided by crunchbase