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Madrigal Pharmaceuticals · 7 hours ago

Director, Global Health Economics & Outcomes Research

Conshohocken, PA

Full-time

Hybrid

Director/Executive

$224K/yr - $274K/yr

12+ years exp

Madrigal Pharmaceuticals is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH). The Director, Global Health Economics & Outcomes Research will lead the GHEOR strategy to optimize patient access, pricing, and reimbursement for Madrigal's medicines, particularly focusing on evidence generation and market access initiatives.

BiopharmaBiotechnologyMedical DevicePharmaceutical

Responsibilities

Lead the evidence generation strategy for Rezdiffra with HQ-based stakeholders in partnership with the cross-functional matrix team

Integrate input from US and international teams into a comprehensive evidence strategy to support market access, reimbursement, and lifecycle management

Design and execute HEOR studies including network meta-analyses and real-world studies, from concept through publication

Develop launch and HTA deliverables such as value dossiers, systematic literature reviews, economic models, and innovative tools to support payer engagement, reimbursement, and access

Provide strategic input into clinical trial design to support payer and regulatory decisions

Partner with internal stakeholders to ensure appropriate dissemination of HEOR materials per regulatory guidance and internal SOPs

Develop strategic partnerships and research collaborations with key external experts healthcare policymakers payers and academic and community oncology settings to support asset strategies

Support the GHEOR budget planning forecasting and allocation to ensure efficient use of resources across US and international initiatives

Manage external vendor contracts and timelines to ensure project deliverables are completed on time within scope and within budget

Foster continuous development through mentoring and training

Align Publications activities with strategic objectives and tactical plans

Ensure all activities comply with company SOPs, industry standards, and applicable regulations

Uphold the highest ethical standards in all external engagements

Willingness to travel up to 30%, primarily in the US, with occasional international travel for conferences or collaboration with all GHEOR teams

Ability to work across international time zones as needed

Qualification

Health EconomicsHealth Technology AssessmentReal-World EvidenceEconomic ModelingStatistical AnalysisProject ManagementInterpersonal SkillsBudget ManagementCommunication SkillsTeam LeadershipProblem-SolvingCollaborationMentoring

Required

Graduate degree in health economics, epidemiology, health services research, or a related field

12-15+ years of HEOR or related experience with 7+ years with PhD

Direct experience with US health technology assessment (HTA) and value assessment bodies (e.g., ICER) and familiarity with select international HTA agencies (e.g., NICE, CADTH)

Deep expertise in health services research methods, including economic modeling, patient-reported outcomes (PROs), statistics, and real-world evidence studies

Proven ability to independently design, execute, and manage complex non-interventional studies in the US and internationally

Strong understanding of the US drug development process and payer landscape

Excellent interpersonal and influencing skills to engage multiple internal and external stakeholders across cross-functional and matrixed teams

Execution-focused and highly organized, with strong project management skills in budgeting, contracting, vendor oversight, and the ability to manage multiple priorities under tight timelines

Exceptional written and verbal communication skills in English, with experience preparing technical and value-based materials for diverse audiences

Demonstrated ability to assess and prioritize projects based on business value, with a proactive approach to problem-solving and adapting to change

High proficiency with project management systems, Medical Affairs dashboards, CRM platforms, and enterprise collaboration tools (e.g., Veeva, Microsoft Office Suite, SharePoint, Teams, Zoom)