Rhythm Pharmaceuticals Inc. · 1 month ago
Vice President, Non-Clinical Research
Boston, MA
Full-time
Hybrid
Director/Executive
$260K/yr - $360K/yr
15+ years expRhythm Pharmaceuticals Inc. is a global biopharmaceutical company focused on transforming the lives of patients with rare neuroendocrine diseases. They are seeking a Vice President of Non-Clinical Research to provide strategic leadership across non-clinical functions and oversee the development of small molecule therapies. This role requires collaboration with senior leaders to align scientific priorities with corporate objectives and to drive innovative research initiatives.
BiotechnologyPharmaceuticalTherapeutics
Responsibilities
Provide strategic leadership for all non-clinical functions, including toxicology, clinical pharmacology, and exploratory biology
Drive exploratory research initiatives to elucidate mechanisms of action, identify new therapeutic opportunities, and inform lifecycle management strategies
Ensure a translational approach to research, integrating non-clinical and clinical insights to optimize development strategies
Partner closely with the CSO and executive leadership to shape overall scientific strategy and ensure alignment with corporate objectives
Collaborate with senior leaders across clinical development, regulatory affairs, data sciences, and commercial to drive cross-functional decision-making
Oversee the design, execution, and interpretation of non-clinical studies supporting IND, early clinical development, and regulatory submissions
Represent non-clinical research in regulatory interactions and contribute to the preparation and review of submission documents
Build and mentor a high-performing team, ensuring scientific excellence and operational rigor
Stay abreast of emerging science and regulatory trends to maintain a competitive edge in rare disease and neuroendocrine drug development
Qualification
Required
Ph.D., M.D., D.V.M., or equivalent in Pharmacology, Toxicology, Biology, or related discipline
15+ years of experience in pharmaceutical or biotechnology R&D, with significant leadership responsibility in non-clinical development
Experience of early stage clinical development
Track record of successful IND and NDA filings
Demonstrated expertise in obesity, metabolism, and neuroendocrinology
Proven ability to translate non-clinical findings into clinical strategy and influence portfolio decisions
Deep understanding of regulatory requirements for non-clinical development and experience engaging with global health authorities
Exceptional ability to influence, collaborate, and communicate across all levels of the organization
Experience leading multi-disciplinary teams in a matrixed environment
Entrepreneurial mindset with a passion for innovation and patient impact
Strong scientific curiosity and ability to translate emerging biology into actionable development strategies
Preferred
Experience in rare disease drug development strongly preferred
Benefits
A discretionary annual bonus may be available based on individual and company performance.
This role may be eligible for benefits and other compensation such as restricted stock units.
Company
Rhythm Pharmaceuticals Inc.
Rhythm Pharmaceuticals is a global, commercial-stage biopharmaceutical company focused on transforming the lives of patients with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.
201-500 employees
H1B Sponsorship
Rhythm Pharmaceuticals Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2024 (1)
2023 (1)
2022 (4)
Funding
Current Stage
Public CompanyTotal Funding
$1.22BKey Investors
HealthCare Royalty Partners
2025-07-10Post Ipo Equity· $175M
2024-04-01Post Ipo Debt· $150M
2022-09-14Post Ipo Equity· $124.8M
Leadership Team
Elisabeth Crönert-Bendell
SVP, Head of Strategy
Recent News
2026-01-11
Company data provided by crunchbase