BBOT · 7 hours ago
Senior Research Associate
South San Francisco, CA
Full-time
Hybrid
Mid, Senior Level
$98K/yr - $112K/yr
3+ years expBBOT is a clinical-stage biopharmaceutical company focused on developing novel small molecule therapeutics for cancer. The Senior Research Associate will play a critical role in the discovery and development of cancer therapeutics, conducting experiments to advance understanding of cancer biology and support drug discovery programs.
Biotechnology
Responsibilities
Play a critical intellectual and technical role in the discovery and development of novel small molecule cancer therapeutics
Independently design, conduct, and analyze experiments to advance our understanding of cancer biology and propel drug discovery programs across our oncology pipeline
Execute experiments (biochemical and cell-based assays) to assess the inhibition or activation of cell signaling in the oncology setting, including in response to small molecule inhibitors
Conduct compound screening (including medium- and high-throughput studies) to identify leads and potential combination therapies
Develop novel tools (such as engineered cell lines, i.e. CRISPR, overexpression, shRNA) and assays as needed to support the group’s discovery mission
Develop and optimize biomarker assays to address critical clinical development questions such as target engagement, predictive biomarkers, and mechanisms of drug resistance
Communicate your findings across seniority levels within and beyond BBOT
Collaborate closely with colleagues across scientific functions and departments, providing key scientific expertise and guidance in an interdisciplinary environment
Provide scientific and technical leadership to junior team members
Keep complete and timely records in electronic lab notebooks
Qualification
Required
B.A./B.S. + 5 years industry experience or M.S.+ 3 years' industry experience in a cell/molecular biology laboratory within an oncology setting
Broad knowledge of cancer biology and independence in critical thinking and scientific achievement
Experience with a broad range of cellular and biochemical techniques, including mammalian tumor cell culture and engineering, CRISPR, si/shRNA, immuno-blotting, NGS, IF/IHC, Flow cytometry, and MSD
Strong problem-solving skills and a commitment to continuous learning and development
Ability to excel in a highly-collaborative and innovative environment
Preferred
Research experience in oncology drug discovery project teams, adherent and suspension cancer cell-based assay design, and assay development is advantageous
Benefits
Annual bonus
Stock-based long-term incentives
Medical, dental, and vision benefits
Retirement
Wellness stipend
Flexible time off
Company
BBOT
BBOT (BridgeBio Oncology Therapeutics) is a clinical-stage biopharmaceutical company advancing a next generation pipeline of novel small molecule therapeutics targeting RAS and PI3K malignancies.
51-200 employees
H1B Sponsorship
BBOT has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (1)
Funding
Current Stage
Growth StageCompany data provided by crunchbase