Legend Biotech · 2 days ago
Associate Scientific Director, Medical Affairs – Real World Evidence (RWE) Generation
United States
Full-time
Remote
Senior Level
5+ years expLegend Biotech is a global biotechnology company dedicated to treating life-threatening diseases. They are seeking an Associate Scientific Director to supervise the Real World Evidence strategy and evidence generation initiatives, focusing on study design and execution to support medical adoption and product differentiation.
BiotechnologyHealth CareLife ScienceOncologyTherapeutics
Responsibilities
Lead the development and execution of RWE generation to address evidence needs in line with Legend Medical Affairs objectives
Formulate research questions, develop study protocols, and design robust methodologies to generate impactful real-world data
Oversee all data generation activities, including MA led Phase IV studies, RWE studies, Investigator Initiated Studies (IIS), and collaborative research
Manage projects from strategy through execution and dissemination (internal and external)
Conduct annual data gap analyses to identify high-value medical affairs-driven studies
Provide leadership in lifecycle evidence management and ensure timely initiation and completion of prioritized studies
Manage project budgets, ensuring efficient resource allocation, vendor management and timely delivery within established financial parameters
Collaborate with internal teams (Clinical Development, Regulatory, Commercial) and external partners to maximize evidence generation and address emerging data needs
Oversee all aspects of study management, including enrollment, milestone tracking, and reporting progress to stakeholders
Represent Legend at relevant internal and external meetings, as well as, congresses, workshops, investigator meetings and other scientific engagements
Qualification
Required
Advanced terminal degree (MD, PharmD, PhD) or other advanced medical degree (NP, PA, etc.) preferred
Minimum 5 years of experience in medical affairs and/or clinical research required, with preference for a track record in RWE strategy and evidence generation
Understanding of research methodologies, protocol development, data analysis, and interpretation of real-world data
Familiarity with regulatory and compliance requirements in RWE research
Demonstrated success in managing complex projects and budgets, and working in cross-functional teams in a matrix environment with a results focused attitude
Excellent written and verbal communication skills, with the ability to translate complex scientific concepts into actionable insights for diverse audiences
Demonstrated proficiency with the most current computer operating systems, Microsoft Office 2013 (particularly Outlook, Word, Excel, and PowerPoint)
SharePoint, Adobe Acrobat Professional, Concur, Veeva and other PC-based applications
Familiar with AI based platforms including Copilot
Benefits
Medical, dental, and vision insurance
401(k)-retirement plan with company match that vest fully on day one
Equity and stock options
Eight weeks of paid parental leave after just three months of employment
Paid time off policy that includes vacation days, personal days, sick time, 11 company holidays, and 3 floating holidays
Flexible spending and health savings accounts
Life and AD&D insurance
Short- and long-term disability coverage
Legal assistance
Supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance
Commuter benefits
Family planning and care resources
Well-being initiatives
Peer-to-peer recognition programs
Company
Legend Biotech
Legend Biotech is a biopharmaceutical company that develops and commercializes novel cell therapies for oncology.
1001-5000 employees
H1B Sponsorship
Legend Biotech has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (30)
2024 (11)
2023 (14)
2022 (7)
2021 (6)
2020 (13)
Funding
Current Stage
Public CompanyTotal Funding
$750.45M2023-05-05Post Ipo Equity· $350M
2022-07-25Post Ipo Equity· $250M
2020-06-05IPO
Leadership Team
Carlos Santos
Chief Financial Officer
Alan Bash
President, CARVYKTI
Recent News
2025-12-18
thefly.com
2025-12-09
Company data provided by crunchbase