Maze Therapeutics · 2 months ago
Senior Medical Director
South San Francisco, CA
Full-time
Onsite
Senior Level
$338K/yr - $412K/yr
6+ years expMaze Therapeutics is a clinical-stage biopharmaceutical company focused on developing precision medicines for patients with renal and cardiovascular diseases. The Senior Medical Director will lead the clinical development strategy for the APOL1 program, overseeing early-stage trials and collaborating with various stakeholders to drive innovative solutions for chronic kidney disease.
BiopharmaBiotechnologyGeneticsTherapeutics
Responsibilities
Lead the design, execution, and analysis of clinical trials for the APOL1 program and other early-stage clinical assets at Maze
Author and review clinical-regulatory documents, including protocols and amendments, informed consents, study reports, and SAPs
Prepare and deliver scientific presentations and other communication materials for internal and external stakeholders, including investigators and other Maze collaborators
Engage with scientific thought leaders and patient advocacy groups to gain insights to inform clinical development plans and build awareness and enthusiasm for the Maze pipeline assets
Partner with Clinical Development Operations to identify and select study investigators and sites and build strong professional relationships with study investigators
Partner with Clinical Development Operations to identify, select, and oversee vendors and CROs to support program needs
Develop and integrate timelines and budgets for clinical activities with overall company timelines and goals, in close coordination with project management, CMC, nonclinical development, regulatory affairs, and other stakeholders
Qualification
Required
MD with 6+ years of drug development industry experience
Board eligibility/certification and clinical experience in internal medicine and/or pediatrics
Experience as a clinical study medical monitor
Experience with the preparation and submission of scientific publications, study protocols, Investigator Brochures, and other clinical-regulatory documents
Experience in the planning and oversight of early-stage and/or registration-enabling clinical development programs including CRO and site selection and relationship building with investigators/site study staff, patient advocacy groups, and other third parties
Demonstrated knowledge and experience in the design and conduct of clinical trials and clinical data analysis and interpretation, particularly Phase 2 trials
Experience leading a cross-functional study team
Committed to nurturing relationships with investigators, site study staff, patient advocacy groups, and other third parties to support the clinical programs and broader Maze objectives
Exceptional organizational, analytical, and communication skills, enabling you to translate corporate objectives into actionable plans that consistently deliver high-quality data on time and within budget
A positive and enthusiastic disposition, adaptability to changing environments, and unwavering personal and ethical standards in pursuit of corporate goals
Willingness to travel domestically and internationally (up to 20%) for vendor visits, industry conferences, regulatory meetings, advisory boards, and other essential gatherings
Preferred
Additional clinical or research experience in nephrology or cardiometabolic diseases
Benefits
Competitive medical, dental, and vision insurance
Mental health offerings
Equity incentive plan
401(k) program with employer match
Generous holiday and PTO policy
Company
Maze Therapeutics
Maze Therapeutics is a biotechnology company that develops precision medicines for renal, cardiovascular, and metabolic diseases.
51-200 employees
H1B Sponsorship
Maze Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (3)
2023 (2)
2022 (5)
2021 (3)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$646MKey Investors
Matrix Capital ManagementCity Hill Ventures
2025-09-11Post Ipo Equity· $150M
2025-01-31IPO
2024-12-03Series D· $115M
Leadership Team
Jason Coloma
Chief Executive Officer
Misbah Tahir
Chief Financial Officer
Recent News
General Catalyst
2026-01-13
2026-01-06
Maze Therapeutics, Inc.
2025-11-09
Company data provided by crunchbase