Generate:Biomedicines · 15 hours ago
Principal Cloud Engineer
Somerville, MA
Full-time
Hybrid
Lead/Staff
$168K/yr - $235K/yr
10+ years expGenerate:Biomedicines is a therapeutics company pioneering Generative Biology™ to create breakthrough medicines. They are seeking a Principal Cloud Engineer to design, develop, and maintain hybrid technology platforms, collaborating with cross-functional teams to integrate cloud services with on-premises systems and applications.
Artificial Intelligence (AI)BiotechnologyHealth CareMedicalProduct Research
Responsibilities
Capture product and security requirements and translate them within integrated application and platform components — defining network boundaries, least-privilege IAM trust/policies in a multi-account environment, Terraform modules with Terragrunt supplied inputs, data access patterns, and GitOps promotion — while documenting and communicating trade-offs, SLOs, and compliance constraints
Design, build, and maintain GitLab CI/CD with OIDC to build and push containers, deploy using Helm and Argo CD, while implementing end-to-end identity and secret flows (GitLab → AWS IAM → Kubernetes IRSA/ServiceAccounts → AWS Secrets Manager) for cross-account, auditable deployments with safe promotion/rollback to deliver applied architecture
Capture product and security requirements and translate them within integrated application and platform components — defining network boundaries, least-privilege IAM trust/policies in a multi-account environment, Terraform modules with Terragrunt supplied inputs, data access patterns, and GitOps promotion — while documenting and communicating trade-offs, SLOs, and compliance constraints
As an ongoing product and service owner-- capture, measure, analyze, and monitor platform resource efficiency and reliability using tools like OTEL, DataDog, and CloudWatch, and apply creative solutions for continual evolution and efficiency improvements
Create and iterate technical solutions leveraging organization-wide best practices and policies covering reusable Terraform modules, Helm chart templates, GitLab CI !include jobs, and other high level application deployment patterns that streamline developer experiences at scale while enforcing security and consistency in a highly autonomous, distributed environment
Coordinate effective integration and deployment of emerging solutions, leading design and development of extensible integration paths between SaaS platforms, databases, and legacy applications, including API management and middleware solutions
Identify and resolve integration related issues, including data inconsistencies, communication failures, and performance bottlenecks
Work closely with development teams, system architects, and business stakeholders to ensure integration solutions meet the organization's "best fit" collective outcome requirements
Test and validate emerging solutions and integrations to ensure they function as expected and meet performance, quality, and security standards
Create and maintain detailed technical documentation, including system architecture, design specifications, and integration workflows
Qualification
Required
Bachelor's degree in Computer Science, Information Technology, or a related field
10+ years of experience in application integration, middleware development, or API management
Extensive knowledge of and integration / engineering experience leveraging major cloud providers such as AWS, Azure, or Google Cloud, including integration design with prevailing SaaS platforms and practices
Strong working knowledge around security best practices for cloud environments, including identity and access management, encryption, and vulnerability management
Applied experience in integrating, deploying, and maintaining Enterprise Finance and G&A related solutions, including data flows, data source objects, and prevailing SaaS platforms (such as Netsuite, Coupa, Oracle, SAP)
Experience with version control systems (e.g., Git) and CI/CD pipelines
Strong problem-solving skills, attention to detail, and ability to work in a fast-paced environment
Excellent communication and collaboration skills to work effectively with cross-functional teams
Preferred
Related Master's degree a positive
History of skillsets applied within biotech or life sciences preferred
Benefits
Annual bonus
Equity compensation
Competitive benefits package
Company
Generate:Biomedicines
Pioneering generative biology to create breakthrough therapeutics.
201-500 employees
H1B Sponsorship
Generate:Biomedicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (7)
2024 (12)
2023 (9)
2022 (3)
2021 (2)
2020 (1)
Funding
Current Stage
Growth StageTotal Funding
$693MKey Investors
Samsung Life Science FundAlumni VenturesFlagship Pioneering
2024-12-18Series Unknown
2023-09-14Series C· $273M
2021-11-18Series B· $370M
Leadership Team
Gevorg Grigoryan
Founding CTO
Recent News
2026-02-05
Company data provided by crunchbase