Kardigan · 9 hours ago
Director, Global Portfolio
Kardigan is a heart health company focused on making cardiovascular disease preventable and curable. The Director, Global Portfolio will enable data-driven decision-making across the development pipeline and collaborate with various teams to enhance portfolio governance and strategic planning.
Artificial Intelligence (AI)BiopharmaHealth CareMedical
Responsibilities
In partnership with the Asset Leads, develop forward-looking decision framework and infrastructure/templates to ensure clear scope, alternatives and trade-offs, as well as robust analysis and risk identification
Lead and manage both regular and ad hoc decision forums, ensuring clear supporting materials, outputs, and organizational communication
Partner with Finance in developing dynamic budgets across assets and portfolio to facilitate trade-off discussions and scenario planning
Drive annual portfolio planning exercise in conjunction with annual strategic plan
Provide as-needed support for creation of portfolio materials required for Board of Directors and other executive level discussions
Related to the above responsibilities, develop and maintain clear processes and templates to facilitate planning, budgeting, and portfolio decision exercises
Partner with the VP of Portfolio & Program Management to continually evolve best practices, seeking cross-functional input and communicating best practices across the org
Qualification
Required
BA or BS, with preference for advanced degree, eg MBA or MA/PhD in scientific area
8+ years of relevant industry experience with a focus on portfolio management, complex scenario analysis, and strategic planning OR 5+ years of experience in strategic management consulting with focus on biopharma and exposure to portfolio-related work
Familiarity with business case modeling and valuation methodologies, such as Net Present Value (NPV)
Understanding of clinical development principles, including common trade-offs and statistical considerations
Broad knowledge of the drug development lifecycle and the roles of cross-functional partners (e.g., Research, Clinical, Regulatory, CMC)
Strong capability in complex scenario analysis and strategic trade-off evaluation
Demonstrated ability to distill complex issues and communicate clearly with executive leadership
Experience driving structured decision-making and influencing senior stakeholders
Experience communicating with executive teams to drive robust decision-making and clear communication processes
Ability to lead workstreams and influence cross-functionally
Strong strategic and technical understanding; strong analytical skills and ability to anticipate operational issues and risks, and to proactively recommend mitigations and solutions
Initiative/self-starter with a continuous improvement mindset and demonstrated experience managing across multiple functions and teams
Strong work ethic with a sense of urgency and demonstrated ability to consistently deliver high quality output
Excellent written and oral communication skills; comfortable interacting and communicating with individuals at all levels of the organization
Detail oriented with ability to manage multiple priorities
Strong sense of resilience and comfortable operating in a fast-paced, dynamic, start-up environment
Flexibility to travel as needed
Company
Kardigan
Kardigan develops personalized medicines using AI and data to target and treat the root causes of cardiovascular diseases.
Funding
Current Stage
Growth StageTotal Funding
$554M2025-10-14Series B· $254M
2025-01-10Series A· $300M
Recent News
2025-12-16
2025-11-19
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