Mount Sinai Health System · 2 months ago
Postdoctoral Fellow-MSH-30030-279
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, and they are seeking a Postdoctoral Fellow to engage in translational research projects studying host-pathogen interactions and host-vaccine responses. The role involves conducting research with preclinical animal models and performing various technical duties including immune profiling and serological assays.
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Responsibilities
The postdoc will be involved in translational research projects that study host-pathogen interactions and host-vaccine responses in preclinical animal models
The research projects include work with guinea pigs, hamsters, mice and human primary cell cultures in BSL2/3/3+ facilities with SARS-CoV-2 and influenza virus
The aim of these studies is to find correlates of protection and understand host immune responses to viral infection and vaccination in different models
Special focus will be on immune profiling of mouse lungs in mice with skewed host immune responses upon respiratory infections
This work will be done at bio safety levels 2 (influenza virus) and 3 (SARS-CoV-2) in the lab
Hamster intranasal vaccination
Adjuvant formulation and vaccine admixing
Virus titration from nasal turbinates and lungs in preclinical animal models
Setting up preclinical infection models with influenza virus and coronaviruses
Serological assays (ELISA, microneutralization assays, ADCC assays, ADCP assays)
Cellular mediated immunity assays (ELISPOT, flow cytometry)
(Single cell) immune profiling (flow cytometry, single cell and bulk RNAseq, luminex cytokine ELISA, …) and assist with multi-OMICS data acquisition and analysis
Qualification
Required
PhD required
Experience with handling mice in BSL2 environments
Sample preparation for OMICS data generation
Experience with serological assays (ELISA) and single cell techniques (flow cytometry, RNA seq,… )
OMICs data analysis with standard analysis pipelines
Company
Mount Sinai Health System
Mount Sinai Health System delivers integrated medical care, research, and medical education through its network.
H1B Sponsorship
Mount Sinai Health System has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)
Funding
Current Stage
Late StageTotal Funding
$41.9MKey Investors
National Institutes of HealthHearst Health Prize.Multiple Myeloma Research Foundation
2024-11-11Grant· $7M
2024-06-06Grant· $0.1M
2023-11-02Grant· $7M
Leadership Team
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2026-01-08
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