Eikon Therapeutics · 10 hours ago
Principal Scientist, Computational Biology
Millbrae, CA
Full-time
Onsite
Lead/Staff
$170K/yr - $185K/yr
10+ years expEikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. The Principal Scientist in Computational Biology will drive early drug discovery efforts by collaborating with discovery scientists to evaluate experiments and identify new drug targets. This role requires a strong analytical background and the ability to mentor junior scientists while contributing to scientific publications and presentations.
BiotechnologyHealth CareLife ScienceMedical
Responsibilities
Use computational approaches to drive drug discovery programs forward in close collaboration with experimentalists throughout Eikon’s target portfolio
Apply statistical, biological, and experimental expertise to evaluate complex experiments and distill information from diverse sources to reach relevant and testable biological conclusions
Identify innovative analytical approaches to answering key biological questions, perform analyses to define their appropriate use, and apply these approaches to further therapeutic programs
Collaborate with informaticists and engineers to prototype new analytical approaches and broadly enable computational capabilities
Mentor junior scientists across functions by providing an example of principled, data-driven problem solving that is supported by deep engagement with underlying biological questions
Contribute to the preparation of scientific publications, presentations, and grant proposals, showcasing the impact of bioinformatics analyses on advancing scientific knowledge
Qualification
Required
PhD or equivalent in a computationally-aligned field plus 10 years' relevant industry experience; minimum with 5 years' experience in drug discovery
Excellent interpersonal, written, and verbal communication skills, with significant experience collaborating closely with experimental teams and providing mentorship to junior scientists
Strong practical expertise in the design, evaluation, and integration of high throughput experiments, as well as deep understanding of the relevant associated statistical techniques
Expertise using one or more high level programming language (e.g. R, Python, or similar) to solve biological problems; well versed in modern coding and computing best practices such as cloud deployment, version control, containerization, etc
Substantial problem-solving skills and creativity as applied to drug discovery questions; experience performing in-depth analysis of experiments, biobanks and patient consortium data to validate known biology and nominate new targets
Preferred
Significant expertise in oncology, neuroscience, methodological development, biomarker discovery, and/or advanced imaging applications
Benefits
401k plan with company matching
Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)
Mental health and wellness benefits
Weeklong summer and winter holiday shutdowns
Generous paid time off and holiday policies
Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee-paid life/AD&D policies
Enhanced parental leave benefit
Daily subsidized lunch program when on-site
Company
Eikon Therapeutics
Eikon Therapeutics is a biopharmaceutical company that develops live-cell resolution microscopy and engineering for drug discovery.
201-500 employees
H1B Sponsorship
Eikon Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (10)
2024 (19)
2023 (7)
2022 (3)
2021 (1)
Funding
Current Stage
Late StageTotal Funding
$1.12BKey Investors
The Column Group
2025-02-26Series D· $350.7M
2023-06-01Series C· $106M
2022-01-06Series B· $518M
Leadership Team
Roger Perlmutter
Chairman, President, and CEO
Michael Klobuchar
Chief Operating Officer
Recent News
General Catalyst
2025-12-26
2025-12-02
Company data provided by crunchbase