Scientist/Senior Scientist, Antibody Engineering jobs in United States
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Arrowhead Pharmaceuticals · 2 hours ago

Scientist/Senior Scientist, Antibody Engineering

positionSan Diego, CA
timeFull-time
remoteOnsite
seniorityMid, Senior Level
money$120K/yr - $150K/yr

Arrowhead Pharmaceuticals is a clinical stage biopharmaceutical company focused on developing innovative drugs for genetic diseases. The successful candidate will play a key role in antibody engineering to support platform development and drug delivery initiatives, requiring extensive hands-on experience in phage display and antibody characterization.

BiotechnologyHealth CareNanotechnologyPharmaceutical
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Comp. & BenefitsbadNo H1Bnote

Responsibilities

Design and construct mutant phage libraries for antibody affinity maturation or humanization
Perform molecular cloning, mutagenesis, antibody gene assembly, and expression vector design
Express and purify recombinant antibodies using bacterial and mammalian expression systems
Perform binding, specific and in vitro functional assays
Collaborate with cross-functional project teams to advance lead antibodies through drug development stages
Maintain accurate documentation and present findings at internal meetings

Qualification

Phage display technologyMolecular cloningAntibody engineeringAntibody purificationAnalytical skillsCommunication skillsCollaboration skillsProblem-solving skills

Required

Ph.D. in Biology, Biochemistry, Molecular Biology, or a related field
Hands-on experience with phage display technology for antibody engineering
Proficiency in molecular cloning, PCR, and mutagenesis
Experience with antibody expression and purification using E. coli, HEK293, and CHO systems
Strong analytical and problem-solving skills, with the ability to troubleshoot experiments independently
Excellent record-keeping, communication, and collaboration skills
Proven ability to adapt to fast pace and evolving research priorities
Track record of scientific productivity, including peer-reviewed publications, conference presentations, or patents
Additional experience in molecular biology and/or antibody discovery is highly desirable

Preferred

Industry or postdoc experience

Benefits

Competitive salaries
Excellent benefit package

Company

Arrowhead Pharmaceuticals

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Arrowhead Pharmaceuticals is a biotechnology company that focuses on the development of medicine to treat diseases with a genetic origin.
dateFounded in 1989
location
Pasadena, California, USA
people-size501-1000 employees
web-link
http://arrowheadpharma.com/

Funding

Current Stage
Public Company
Total Funding
$1.62B
Key Investors
Sarepta TherapeuticsSixth StreetSilence Therapeutics
2024-11-26Post Ipo Equity· $325M
2024-08-08Post Ipo Debt· $400M
2024-01-03Post Ipo Equity· $450M

Leadership Team

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Christopher Anzalone
President and Chief Executive Officer
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Bruce Given
Chief Operating Officer
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Recent News

MedCity News
Fatal Complication of Stem Cell Transplants Gets Its First FDA-Approved Therapy
2025-12-27
Los Angeles Business Journal
2025 Year in Review
2025-12-24
Morningstar.com
Arrowhead Pharmaceuticals Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)
2025-12-16
Company data provided by crunchbase