Scientist/Senior Scientist, Antibody Engineering jobs in United States
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Arrowhead Pharmaceuticals · 2 months ago

Scientist/Senior Scientist, Antibody Engineering

Arrowhead Pharmaceuticals, Inc. is a clinical stage biopharmaceutical company focused on developing innovative drugs for diseases with a genetic basis. The successful candidate will play a key role in antibody engineering to support platform development and drug delivery initiatives, requiring extensive hands-on experience in phage display and molecular biology.

BiotechnologyHealth CareNanotechnologyPharmaceutical
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Comp. & Benefits
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Responsibilities

Design and construct mutant phage libraries for antibody affinity maturation or humanization
Perform molecular cloning, mutagenesis, antibody gene assembly, and expression vector design
Express and purify recombinant antibodies using bacterial and mammalian expression systems
Perform binding, specific and in vitro functional assays
Collaborate with cross-functional project teams to advance lead antibodies through drug development stages
Maintain accurate documentation and present findings at internal meetings

Qualification

Phage display technologyMolecular cloningAntibody engineeringAntibody purificationAnalytical skillsCommunication skillsCollaboration skillsProblem-solving skills

Required

Ph.D. in Biology, Biochemistry, Molecular Biology, or a related field
Hands-on experience with phage display technology for antibody engineering
Proficiency in molecular cloning, PCR, and mutagenesis
Experience with antibody expression and purification using E. coli, HEK293, and CHO systems
Strong analytical and problem-solving skills, with the ability to troubleshoot experiments independently
Excellent record-keeping, communication, and collaboration skills
Proven ability to adapt to fast pace and evolving research priorities
Track record of scientific productivity, including peer-reviewed publications, conference presentations, or patents

Preferred

Industry or postdoc experience
Additional experience in molecular biology and/or antibody discovery is highly desirable

Benefits

Competitive salaries
Excellent benefit package

Company

Arrowhead Pharmaceuticals

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Arrowhead Pharmaceuticals is a biotechnology company that focuses on the development of medicine to treat diseases with a genetic origin.

Funding

Current Stage
Public Company
Total Funding
$2.45B
Key Investors
Sarepta TherapeuticsSixth StreetSilence Therapeutics
2026-01-07Post Ipo Equity· $200M
2026-01-07Post Ipo Debt· $625M
2024-11-26Post Ipo Equity· $325M

Leadership Team

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Christopher Anzalone
President and Chief Executive Officer
Company data provided by crunchbase