In Vivo Scientist, Oncology jobs in United States
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Pattern Biosciences · 2 months ago

In Vivo Scientist, Oncology

positionSouth San Francisco
timeFull-time
remoteOnsite
seniorityMid Level
date3+ years exp

Pattern Biosciences is dedicated to curing cancer and saving lives through innovative biological circuits and AAV-based therapies. They are seeking an In Vivo Scientist to design and execute preclinical studies for AAV-based cancer therapeutics, ensuring scientific rigor and compliance with regulations.

BiotechnologyGeneticsHealth CareTherapeutics

Responsibilities

Design and execute preclinical in vivo studies in collaboration with discovery and data scientists, develop timelines and action plans to meet company goals
Choose appropriate in vivo models and develop protocols with relevant endpoints for evaluating the mechanism of action, efficacy, and safety of therapeutic candidates
Perform hands-on in vivo experiments, including orthotopic tumor cell implantation, IV, IP and SC injections, in vivo imaging, and animal welfare monitoring
Perform biological sample collection and processing, MACS/FACS cell sorting, immune cell profiling using multicolor flow cytometry, immunogenicity testing using ELISA and ELISPOT, and cell-based functional assays
Generate, document, analyze and interpret experimental data to support critical decisions
Manage external laboratories and partners

Qualification

Vivo pharmacologyImmuno-oncologyMurine tumor modelsMulti-color flow cytometryCell sortingTissue handlingExperimental designCommunicationDetail-orientedOrganizational skills

Required

PhD in Life Sciences with specialization in oncology or immunology
At least 3 years of hands-on experience working with murine tumor models in an industry and/or academic setting
Demonstrated independent ability to design, execute and interpret experimental data
Demonstrated experience in in vivo procedures, such as rodent surgery and IV dosing
Experience with tissue handling and processing, cell sorting, multi-color flow cytometry and cytokine profiling
Proficiency in mammalian cell and tissue culture
Detail-oriented, with strong organizational and record-keeping skills
Excellent communication skills and ability to collaborate effectively in a cross-functional team

Preferred

Experience with IHC and ISH is a plus
Experience working in a GLP or regulatory-compliant environment is a plus

Company

Pattern Biosciences

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Pattern BioSciences is an early-stage biotechnology start up company and an ETH Zurich spin-off.
dateFounded in 2018
location
Basel, Basel-Stadt, CHE
people-size2-10 employees
web-link
https://www.patternbio.com/

Funding

Current Stage
Early Stage
Total Funding
$0.08M
2023-09-01Pre Seed
2019-01-01Grant· $0.08M
Company data provided by crunchbase