Revolution Medicines · 11 hours ago
Senior Clinical Data Manager
San Francisco Bay Area
Full-time
Onsite
Senior Level
$138K/yr - $172K/yr
5+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The Senior Clinical Data Manager will oversee the data management process for clinical trials, ensuring timely deliverables and effective coordination with study teams and CROs.
Health CareLife ScienceMedical
Responsibilities
Represents data management in study team meetings, able to facilitate and provide data management updates and/or input when appropriate
Manages data management timelines to coordinate and synchronize deliverables with the overall study timelines
Generates and/or reviews/approves study documents (e.g. Data Management Plans, Case Report Forms, DB build specifications, data transfer specifications, SAE and/or external data reconciliation plans, coding conventions, laboratory data handling plan, study protocols)
Reviews protocols for appropriate data capture including electronic Case Report Form (eCRF) design and external data vendors’ systems
Provides oversight of database set-up/migrations/updates including coordinating and performing UAT
Leads the development of internal Data Review Plan and coordinates cross functional team data listing review
Coordinates the internal medical coding review
Performs ad hoc and scheduled data listing review and generates/resolves queries in EDC
Performs external data reconciliation against EDC
Performs Serious AE reconciliation according to SOPs and guidelines, as applicable
Executes and/or distributes data management metrics, listings, and reports
Provides oversight of data management CRO/service providers including manages and monitors the progress of data management activities with CROs and/or other service providers on assigned studies; build effective relationships with CRO/service provider counterparts
Reviews and provides feedback to the clinical team on other study documents e.g., Clinical Monitoring plans and vendor specifications
Provides training on the EDC system and/or CRF completion guidelines and EDC system to internal or external study team members, as needed
Proactively identifies potential study issues/risks and recommends/implements solutions
Maintains study DM related documents/files for inspection readiness
Provides DM support to Statisticians and Statistical Programmers in production of clinical trial reports and other deliverables
Assists with the training of new employees and/or contractors (e.g., clinical data associates and/or junior clinical data managers working on the studies)
Participates in CRO/vendor selection process for outsourced activities
Supports budget and resource planning across assigned projects
Participates in the development, review and implementation of departmental SOPs, templates, and processes
Participates in department or cross-functional initiatives (as needed)
Contributes to a professional working environment through exemplifying RevMed Core Values
Qualification
Required
Bachelor's degree in health sciences, Life Sciences, Mathematics, Computer Sciences, or health-related field
At least five (5) years for Sr. CDM of Data Management experience in the pharmaceutical or biotechnology industry, depth and exposure to DM related tasks considered in lieu of minimum requirement
Requires solid knowledge of clinical data management principles, clinical trials process and regulatory requirements
Good working knowledge of ICH, FDA, and GCP regulations and guidelines
Strong well-rounded technical skills (EDC systems, MS Word, Excel, PowerPoint)
Knowledge of industry standards (CDISC, SDTM, CDASH)
Experience with web-based Electronic Data Capture (EDC), clinical data management systems and industry wide thesauri, such as MedDRA and WHO Drug
Excellent verbal/written and interpersonal skills required for working successfully in a cross-functional team environment
Ability to handle multiple projects and prioritize effectively, well organized and detail oriented
Proven ability to work both independently and in a team setting
Preferred
Bachelor's degree in health sciences, Life Sciences, or health-related field
CRO/Service provider management experience
Prior oncology/solid tumor experience highly desired
Knowledge of industry standards (CDISC, SDTM, CDASH)
Working knowledge of statistical programming packages (e.g. SAS) is a plus
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
2025-12-18
2025-12-18
Company data provided by crunchbase