BridgeBio · 2 hours ago
Sr. Director, Data Science, Patient Identification
San Francisco Bay Area
Full-time
Hybrid
Director/Executive
$260K/yr - $300K/yr
10+ years expBridgeBio is a biotech company focused on developing life-changing medicines for patients with unmet needs. They are seeking a Sr. Director of Data Science to lead data-driven strategies that identify undiagnosed patients and enhance diagnosis processes across their rare disease portfolio.
BiotechnologyHealth CareLife ScienceMedicalPharmaceutical
Responsibilities
Spearhead a high-performing data science function focused on patient identification and provider targeting
Identify, source, and integrate (tokenized) data assets in the pursuit of finding rare disease patients and treating HCPs across the portfolio for BrigeBio companies. Define the vision, priorities, and key success metrics for data science initiatives across multiple rare disease programs
Architect scalable analytical solutions using RWD (claims, EHR, genomics, lab data, imaging, and registry sources)
Define the roadmap for AI/ML innovation, balancing cutting-edge research with production-grade reliability
Build and foster a collaborative, mission-driven culture grounded in an enterprise perspective (use of data and data science work across the organization), precision, urgency, and patient impact
Design predictive models, algorithms, and patient finding tools using real-world data (claims, EMR, lab/genomics). Apply NLP and LLM techniques to extract phenotypic signals from unstructured EMR data
Pioneer new methodologies in AI/ML for patient identification, leveraging subtle clinical and diagnostic patterns. Design and execute experiments with different approaches to patient finding
Build frameworks for model monitoring, retraining, and performance evaluation in real-world deployment environments
Design and deploy supervised and unsupervised models for patient finding, diagnostic acceleration, and disease progression prediction. Translate complex insights into actionable strategies for field execution, engagement planning, and clinical partnerships
Drive the development of robust data pipelines, governance frameworks, and scalable model-serving infrastructure
Evaluate and integrate third-party data (claims, genomics, HCP, diagnostic lab feeds) to enhance model accuracy and reach
Partner with outside vendors and internal resources to operationalize analytics solutions across BridgeBio’s portfolio
Champion best practices in reproducibility, version control, and MLOps
Partner with Commercial, Medical Affairs, and Computational Genomics teams to integrate analytic insights into decision-making
Engage with KOLs and data partners to identify early clinical signals that inform algorithmic models
Establish program-level KPIs, dashboards, and reporting frameworks to track performance and continuously improve model accuracy
Ensure compliance with HIPAA, privacy, and ethical data governance standards
Manage external vendors and partnerships to expand analytic capabilities and accelerate delivery
Qualification
Required
10+ years of experience in data science or analytics within biotech/pharma; 3+ years in a leadership role
Proven expertise in real-world data (RWD) analytics, patient identification, and segmentation across multiple therapeutic areas. Experience with large-scale real-world data (claims, EMR/EHR, lab/genomics, registry, or wearable data)
Experience developing and deploying sophisticated ML/statistical models using large-scale health data. Deep expertise in building predictive and classification models using Python, R, SQL, TensorFlow, PyTorch, or equivalent tools. Strong understanding of feature engineering, model explainability, and ML pipeline automation
Proven success translating analytics into actionable strategies that drive measurable patient or business outcomes
Bachelor's degree in data science, computer science, statistics, or a related quantitative field
Experience in rare disease analytics or patient-finding programs that supported commercial launches or diagnostic initiatives
Preferred
Advanced degree (PhD, MS, MPH) in data science, biostatistics, computer science, or related field
Familiarity with generative AI, LLMs, or graph-based learning applied to healthcare or biomedical data
Benefits
401K with 100% employer match on first 3% & 50% on the next 2%
Employee stock purchase program
Pre-tax commuter benefits
Referral program with $2,500 award for hired referrals
Comprehensive health care with 100% premiums covered - no cost to you and dependents
Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
Hybrid work model - employees have the autonomy in where and how they do their work
Unlimited flexible paid time off - take the time that you need
Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents
Flex spending accounts & company-provided group term life & disability
Subsidized lunch via Forkable on days worked from our office
People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities
Company
BridgeBio
BridgeBio focuses on the development and commercialization of precision medicines for various genetic diseases and cancers.
201-500 employees
H1B Sponsorship
BridgeBio has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2024 (5)
2023 (4)
2022 (4)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$4.9BKey Investors
Blue OwlQatar Investment AuthorityKohlberg Kravis Roberts
2026-01-16Debt Financing· $550M
2025-02-25Post Ipo Debt· $500M
2024-03-04Post Ipo Equity· $250M
Leadership Team
Justin To
CEO, Skeletal Dysplasias (QED Therapeutics)
Neil Kumar
CEO and Founder
Recent News
2026-01-05
2025-12-24
Company data provided by crunchbase