SDSU Research Foundation · 3 months ago
Postdoctoral Research Scholar 0-5 yrs Experience
San Diego, CA
Full-time
Onsite
New Grad, Entry, Mid Level
$5,858.67/mo - $5,858.67/mo
0+ years expSDSU Research Foundation is focused on advancing nucleic acids chemical biology through innovative research. The Postdoctoral Research Scholar will contribute expertise in synthetic organic chemistry and chemical biology to develop fluorescent nucleoside analogues and molecular probes, supporting the advancement of RNA-centered therapeutics.
Higher Education
Responsibilities
Design and carry out multi-step organic syntheses of novel nucleoside / nucleobase analogues and derivative molecules
Develop and apply synthetic chemistry to whole oligonucleotides and nucleic acids
Purify, characterize, and validate synthetic intermediates and final compounds (e.g. NMR, MS, chromatography)
Evaluate photophysical and spectroscopic properties of candidate probes
Work with collaborators and the internal team to integrate synthetic compounds into nucleic acid constructs or assays
Analyze and interpret results; troubleshoot synthetic and analytic challenges
Prepare manuscripts, reports, and presentations; contribute to research planning and strategy
Mentor or train graduate or undergraduate students in synthetic methods and lab practices
Attend lab meetings, seminars, and participate in departmental and university activities as appropriate
Qualification
Required
Deep expertise in synthetic organic chemistry, including reaction design, optimization, purification, and structural characterization
Strong command of spectroscopic methods (¹H/¹³C NMR, mass spectrometry, chromatography, etc.)
Strong problem-solving skills, initiative, intellectual independence, and ability to plan and execute experiments
Excellent written and oral communication skills, ability to document work clearly and present results
Ability and enthusiasm to work in multi-disciplinary, inclusive, and collaborative environments
A doctoral degree in an appropriate field
0-5 years of relevant experience
Preferred
PhD. in organic chemistry, chemical biology, or a related discipline, to be completed before appointment
Demonstrated record of creativity and research productivity (e.g. publications, presentations, successful projects during Ph.D.)
Experience performing multi-step syntheses, purification, and structural verification
Prior experience in nucleic acid chemistry (e.g. oligonucleotide synthesis, nucleobase analogues, nucleoside modification)
Experience working with photophysical, spectroscopic, or biophysical assays (fluorescence spectroscopy, binding assays, etc.)
Experience mentoring or training more junior students or staff
Demonstrated ability to contribute to collaborative projects and to interface with external partners or industry collaborators
An awareness of challenges in probe design (e.g. steric perturbation, fluorescence quenching) and prior examples in literature
Company
SDSU Research Foundation
SDSU Research Foundation (SDSURF) is a non-profit auxiliary organization chartered to further the educational, research, and community service objectives of San Diego State University (SDSU).
1001-5000 employees
H1B Sponsorship
SDSU Research Foundation has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (7)
2024 (3)
2023 (7)
2022 (1)
2021 (3)
2020 (2)
Funding
Current Stage
Late StageLeadership Team
Leslie Levinson
Chief Financial Officer
April Fox
HR Business Partner
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