Neurocrine Biosciences · 2 weeks ago
Sr. Scientist, Immunology/Neuroimmunology
San Diego, CA
Full-time
Onsite
Mid, Senior Level
$111K/yr - $151K/yr
5+ years expNeurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company dedicated to discovering and developing life-changing treatments for patients with neurological disorders. The role involves developing novel drugs and therapeutic approaches targeting inflammation and disease progression in the autoimmune and neuroimmune spaces, while leading cross-functional teams and managing experimental work.
BiotechnologyHealth CarePharmaceutical
Responsibilities
Independent proposal, identification, and validation of novel targets in the immunology space, strategically impacting target discovery and portfolio progression
Utilize cutting edge knowledge, technology and assays to design and execute experiments for validation of new targets, and functional assessment of novel therapeutics
Lead project groups, and work with cross-functional teams to drive project progression and therapeutic development
Conduct and manage in vitro, ex vivo, and in vivo experimental work to support new target discovery projects and assessment of novel therapeutics, both large and small molecule in approach
Effectively convey novel target ideas, project visions and progress to wider functional teams and senior management
Interact in a matrixed, dynamic environment to bring project teams together and progress novel therapeutics forward efficiently
Generate and analyze cellular gene signatures to identify and validate targets/pathways in human and animal tissues
Work with external collaborators and manage external opportunities
Establish and lead external relationships with CRO’s to drive data delivery and external innovation
Other duties as assigned
Qualification
Required
PhD degree in Immunology, Neuroimmunology and/or related science discipline and and some relevant experience; may include postdoc experience OR
MS/MA degree in Biological Sciences preferably related to Immunology, Neuroimmunology, or Pharmacology and 2+ years of similar experience above OR
BS/BA degree in Biology, Life Sciences or related discipline preferably related to immunology/neuroimmunology and 4+ years of experience in the biotech/pharmaceutical industry with exposure to drug discovery
PhD in immunology/neuroimmunology with 0-3 years of relevant experience in industry, OR MS degree in an area related to immunology/neuroimmunology with 5+ years of experience in industry setting, OR BS degree in an area related to immunology/neuroimmunology with 8+ years of experience in industry setting
Demonstrated expertise and scientific achievement in immunology and/or neuroimmunology fields
Expertise in the isolation and culture of human and mouse blood/tissue-derived primary cells, such as PBMC, T cells, B cells, myeloid cells, splenocytes, stromal cells, etc
Expertise in culture of mammalian cell lines and reporter cell lines
Experience in functional immune-based assays, such as cell proliferation, cytokine release, ADCC, MLR, immune cell co-culture, signaling pathway analysis
Experience in core immunology lab techniques, such as high-parameter flow cytometry, MSD & ELISA, qPCR/Nanostring/RNA-seq, DNA/RNA/protein extraction, magnetic-based cell purification, multiplex bead arrays
Demonstrated expertise in the use of in vivo studies and common autoimmune models in rodents, with CRO management as a plus
Experience working with large molecule treatment modalities; small molecule experience is a plus
Proven success managing internal/external lab personnel
Assimilates data and research findings outside of Neurocrine for application to new scientific projects
Strong attention to detail, excellent written and oral communication skills
Proactive, innovative, with good problem-solving skills
Ability to work in a cross functional team and matrix environment
Ability to influence others with or without authority at all levels of the organization
Excellent written, presentation, and verbal communication skills
Demonstrates solid level of understanding project / group goals and methods
Consistently recognizes anomalous and inconsistent results and interprets experimental outcomes
Able to explain the process behind the data and implications of the results
Strong knowledge of one or more scientific disciplines, becoming expert in one discipline
Strong knowledge of scientific principles, methods and techniques
Strong knowledge and demonstrated ability working with a variety of laboratory equipment/tools
Ability to work as part of a team; may train lower levels
Ability to leading teams
Excellent computer skills
Strong communications, problem-solving, analytical thinking skills
Detail oriented yet can see broader picture of scientific impact on team
Ability to meet multiple deadlines, with a high degree of accuracy and efficiency
Strong project management skills
Must have working knowledge of Microsoft Office, Word, and Excel
Advanced multitasking, trouble shooting and deductive reasoning skills required
Benefits
Annual bonus with a target of 20% of the earned base salary
Eligibility to participate in our equity based long term incentive program
Retirement savings plan (with company match)
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans
Company
Neurocrine Biosciences
Neurocrine Biosciences engages in the discovery and development of drugs for the treatment of neurological and endocrine-related diseases.
1001-5000 employees
H1B Sponsorship
Neurocrine Biosciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (16)
2024 (9)
2023 (8)
2022 (2)
2021 (5)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$260MKey Investors
Venrock
2015-02-19Post Ipo Equity· $250M
2009-12-17Post Ipo Equity· $10M
1996-05-31IPO
Leadership Team
Matt Abernethy
Chief Financial Officer
D
Dimitri Grigoriadis
VP, Research
Recent News
2026-01-06
Company data provided by crunchbase