Flagship Pioneering · 14 hours ago
Operating Principal, Summit PBU
Cambridge, MA
Full-time
Onsite
Director/Executive
$220K/yr - $270K/yr
10+ years expFlagship Pioneering is a company that invents and builds platform companies aimed at transforming human health and sustainability. They are seeking an Operating Principal to lead operations and strategy for their NewCos, driving corporate development and partnering with scientific leadership to translate innovative ideas into impactful solutions.
FinanceFinancial ServicesVenture Capital
Responsibilities
Lead strategy and operational planning in one or more NewCos
Drive corporate development initiatives, including partnerships, financings, and strategic alliances, as well as engagement with Board of Directors and other important stakeholders
Engage directly with scientists and company leaders to align technical progress with operational goals
Recruit, develop, and manage high-performing teams across functions
Partner with Flagship central teams (Finance, Talent, Legal/IP, HR) to bring best-in-class infrastructure to each company
Shape and execute operating and long-range plans, ensuring milestones are achieved on time and on budget
Build strong external relationships with investors, partners, and key opinion leaders
Qualification
Required
10+ years of experience in biotech, pharma, or life sciences strategy/operations; prior management consulting a plus
Proven success in strategic, operational, or corporate development leadership, ideally in early-stage biotech
Strong scientific acumen; able to quickly grasp novel science and translate it into plans and execution
Track record of building and motivating high-performing teams
Skilled communicator, able to influence and inspire across investors, partners, and internal teams
Expert problem solver; can bring order to chaos and iterate quickly to find solutions
Entrepreneurial, resilient, and hands-on; able to adapt and execute with urgency; doesn't mind rolling up sleeves and doing what needs to be done to move the ball forward
Preferred
Advanced degree in life sciences or business preferred (PhD, MD, MBA, or equivalent experience)
Benefits
Healthcare coverage
Annual incentive program
Retirement benefits
A broad range of other benefits
Company
Flagship Pioneering
Flagship Pioneering is a venture capital firm that invests in life sciences and healthcare companies.
501-1000 employees
H1B Sponsorship
Flagship Pioneering has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (4)
2023 (4)
2022 (4)
2021 (1)
Funding
Current Stage
Late StageLeadership Team
Noubar Afeyan
Founder and CEO
Chuck Carelli
Chief Financial Officer
Recent News
2026-01-16
2026-01-16
Company data provided by crunchbase