Full Stack - Principal Software Engineer, Drug Discovery jobs in United States
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Genentech ยท 2 weeks ago

Full Stack - Principal Software Engineer, Drug Discovery

positionNew York, NY
timeFull-time
remoteOnsite
seniorityLead/Staff
money$156K/yr - $289K/yr
date10+ years exp

Genentech is a leader in healthcare innovation, focusing on advancing science and ensuring access to healthcare. They are seeking a Principal Software Engineer to lead the design and development of their AI-driven Lab-in-the-Loop platform, which is critical for accelerating drug discovery by integrating experimental data to train predictive AI models.

BiotechnologyLife ScienceManufacturing
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Contribute to the strategic roadmap for the Prescient "Lab-in-the-Loop" platform, guiding product features and technical architecture to maximize AI impact in drug discovery
Take a leading role in the full-stack design and development of scalable, reliable software systems, including crafting responsive and intuitive front-end applications that form the core of our AI/ML platform
Collaborate closely with Machine Learning Scientists, AI Engineers, and experimental specialists, translating complex scientific workflows into intuitive user interfaces, dashboards, and analytics tools with a strong focus on user experience
Explore and implement integrations with novel AI agents and models to enhance platform capabilities and automate complex tasks
Mentor and provide technical guidance to other software engineers on the team, fostering best practices and high-quality engineering

Qualification

Full-stack developmentFront-end frameworksPythonSQLMachine LearningDrug discovery experienceUser experience focusTechnical mentorshipCollaboration skills

Required

10 + years of software engineering work experience, delivering complex, full-stack applications
Proven expertise in front-end development using modern frameworks (e.g., React, Angular) and building intuitive, user-centered interfaces
Intense curiosity about the biology of disease and eagerness to contribute to scientific and computational efforts
Proficiency with Python and SQL

Preferred

Familiarity with ML concepts or frameworks (e.g., PyTorch)
Domain experience in drug discovery, computational biology, bioinformatics and cheminformatics

Benefits

Relocation benefits are available for this job posting
A discretionary annual bonus may be available based on individual and Company performance.

Company

Genentech

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Genentech is a biotechnology research company that specializes in genetic testing and personalized medicines.
dateFounded in 1976
location
South San Francisco, California, USA
people-size10001+ employees
web-link
http://gene.com

H1B Sponsorship

Genentech has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (167)
2024 (148)
2023 (150)
2022 (178)
2021 (121)
2020 (158)

Funding

Current Stage
Public Company
Total Funding
unknown
2009-03-26Acquired
1999-07-20IPO
1976-01-01Series Unknown

Leadership Team

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Ashley Magargee
Chief Executive Officer
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Michael Laird
Vice President, Global MSAT Drug Substance Biologics Technology and Commercial Products Support
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