BillionToOne · 1 day ago
Laboratory Director/Senior Laboratory Director - Oncology
Menlo Park, CA
Full-time
Onsite
Senior Level, Lead/Staff, Director/Executive
$216K/yr - $264K/yr
4+ years expBillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. They are seeking an experienced Molecular Genetics Clinical Laboratory Director – Oncology or Senior Laboratory Director – Oncology to provide technical leadership and oversee the daily operations of their high-complexity oncology clinical laboratory, ensuring accurate test results and regulatory compliance.
BiotechnologyGeneticsHealth DiagnosticsMedical
Responsibilities
Provide technical oversight to ensure high-quality oncology testing and alignment with laboratory and clinical goals
Interpret somatic variant results from Northstar liquid biopsy assays, classify variants, and sign out oncology clinical reports
Troubleshoot technical issues related to oncology workflows, including liquid biopsy sample prep, NGS library preparation, sequencing, and data analysis
Evaluate lab performance, implement process improvements, and promote robust quality assurance systems
Review Non-Conforming Events and CAPAs to ensure timely resolution of issues impacting oncology test performance
Ensure compliance with CLIA, CAP, NYSDOH, and other applicable regulatory standards for oncology assays
Oversee accurate documentation of SOPs, validation reports, QC records, personnel competencies, proficiency testing, and report archives
Collaborate with bioinformatics, R&D, and medical affairs on assay development, interpretation guidelines, and continuous assay optimization
Participate in budget planning and manage lab expenses to ensure financial efficiency while maintaining exceptional quality
Support special projects, including scaling new oncology tests, preparing for inspections, and implementing automation
Serve as a subject matter expert on oncology variant interpretation, including AMP/CAP/NYS guidelines
Qualification
Required
Doctoral degree (PhD, MD, or equivalent) in genetics, molecular biology, or a related field
Board certification (ABMGG, ABP in Molecular Genetic Pathology, or equivalent)
Valid or eligible for California Clinical Laboratory Director license (CGMB, CGMBS, MD/DO licensure) and New York State CoQ in oncology testing
4+ years in a regulated clinical laboratory environment (CLIA/CAP/NYSDOH), with at least 3 years in molecular oncology testing including NGS
Proven leadership in developing, validating, and implementing oncology assays (e.g., somatic mutation panels, methylation assays)
Deep knowledge of cancer genomics, including tumor heterogeneity, somatic driver mutations, and targeted therapies
Experience with variant interpretation databases (COSMIC, OncoKB, ClinVar), IGV, BAM file review, and molecular tumor board participation
Strong analytical, communication, and organizational skills, with a track record of leading teams in high-growth environments
Proficiency with LIMS and oncology-focused bioinformatics tools
Benefits
Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Daily on-site lunches provided from top eateries
A variety of perks on campus (state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)
Generous equity options offering
Corporate bonus program
Industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.)
Company
BillionToOne
BillionToOne is a precision diagnostics company that focuses on genetic testing for disease detection.
501-1000 employees
H1B Sponsorship
BillionToOne has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (10)
2024 (6)
2023 (2)
2022 (2)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$425.9MKey Investors
Premji InvestBridge BankHummingbird Ventures
2025-11-06IPO
2024-06-21Series D· $130M
2022-12-15Series C· $48.5M
Leadership Team
J
Jean Hayden
VP of Operations and Chief of Staff to the CEO
Oguzhan Atay
Co-founder and CEO
Recent News
Norwest
2025-12-31
Company data provided by crunchbase